1) TrkA
酪氨酸蛋白激酶A
1.
Objective To explore the changes of NGF and TrkA expression in the motocortex and corticospinal tract of rat following spinal cord injury.
结果 脊髓损伤后上述部位酪氨酸蛋白激酶A(TrkA)的表达随SCI后动物存活时间的延长明显上调 ,电镜观察发现损伤后的皮质脊髓侧束轴浆内有TrkA免疫反应阳性产物积聚 ,轴膜上亦有免疫反应产物分布 ,且轴索末端有生芽现象 ;皮质脊髓侧束的神经纤维内可见串珠状的NGF免疫反应阳性产物 ,束内NGF阳性胶质细胞亦随动物术后存活时间的延长逐渐增多。
2) Tyrosine protein kinase
酪氨酸蛋白激酶
1.
Relationship between tyrosine protein kinase and synapse plasticity, learning and memory;
酪氨酸蛋白激酶与突触可塑性及学习记忆的关系
2.
· AIM: To study the function of tyrosine protein kinase pathway in ultraviolet induced enhanced PGE2 synthesis in human lens epithelial cells (HLECs).
目的:探讨酪氨酸蛋白激酶途径在紫外线引起的晶状体上皮细胞前列腺素E(2PGE2)合成增加过程中的作用。
3.
Objective: To examine the effect of basic fibroblast growth factor (bFGF) of different concentrations on activitites of tyrosine protein kinase (TPK), protein kinase C(PKC) and extracellular signal regulated protein kinase (ERK) in NIH3T3 cell line and to elucidate the signal pathway in cell proliferation and differentiation.
目的 :观察碱性成纤维细胞生长因子 (bFGF)对NIH3T3细胞酪氨酸蛋白激酶 (TPK)、蛋白激酶C(PKC)及胞外调节蛋白激酶 (ERK)活性的影响 ,探讨其信号转导机制。
3) protein tyrosine kinase
蛋白酪氨酸激酶
1.
Progress of research on the new protein tyrosine kinase inhibitor antitumor drugs;
新型蛋白酪氨酸激酶抑制剂类抗肿瘤药物的研究进展
2.
Effects of protein tyrosine kinase wihin the brainstem nucleus tractus solitarius on the ventilatory responses of peripheral chemoreflex;
孤束核蛋白酪氨酸激酶对外周化学感受性反射呼吸作用的影响
3.
Protein kinase C and protein tyrosine kinase mediate lipopolysaccharide-and cytokine-induced nitric oxide formation in vascular smooth muscle cells of rats;
蛋白激酶C和蛋白酪氨酸激酶介导脂多糖及细胞因子诱导大鼠血管平滑肌细胞一氧化氮的生成(英文)
4) protein tyrosine kinase
酪氨酸蛋白激酶
1.
Effects of Dexamethasone and protein tyrosine kinase inhibitor on tumour necrosis factor alpha and interleukin 1 beta induced IL-8 production from gastric epithelial cell;
地塞米松及酪氨酸蛋白激酶抑制剂对胃上皮细胞白介素-8分泌抑制作用的实验研究
2.
After 24 h,48 h,72 h and 96 h, the OECs been captured, and the activity of protein tyrosine kinase(PTK) was examined by.
目的观察银杏提取液对嗅神经鞘细胞(OECs)中的酪氨酸蛋白激酶(PTK)活性的影响。
3.
Protein tyrosine kinases (PTKs) are the family members of oncoproteins and protooncoproteins which play important roles in the normal proliferation and unusual hyperplasia course.
酪氨酸蛋白激酶(PTKs)是一组酶系,是在正常和异常增殖过程中起重要作用的癌蛋白和原癌蛋白家族中的成员。
5) TPK
酪氨酸蛋白激酶
1.
Method to Determine the Activity of TPK of Tissue Membrane Insulin Receptor;
组织细胞膜胰岛素受体酪氨酸蛋白激酶活力测定方法
2.
Changes of the cytokine and TPK activity in PC_(12) cells after hypoxia injury
缺氧PC_(12)细胞中细胞因子和酪氨酸蛋白激酶活性的变化
3.
Objective To study the effects of TNFα on activity of TPK(tyrosine protein kinase) of the membrane insulin receptor of the muscle and liver in KM mouse.
目的观察肿瘤坏死因子α(TNFα)对KM小鼠骨骼肌和肝细胞膜胰岛素受体酪氨酸蛋白激酶(TPK)活力的影响。
6) protein tyrosine kinases
蛋白酪氨酸激酶
1.
Review on the research development of small molecular protein tyrosine kinases inhibitors;
蛋白酪氨酸激酶小分子抑制剂研究进展
2.
Detection of intracellular phosphorylated protein tyrosine kinases by flow cytometry;
胞内磷酸化蛋白酪氨酸激酶的流式细胞术检测
3.
Expression and functions of protein tyrosine kinases in fibroblast-like synovial cells from rheumatoid arthritis patients;
蛋白酪氨酸激酶在类风湿性关节炎滑膜细胞中的表达和功能
补充资料:酪氨酸蛋白激酶抑制剂
分子式:
CAS号:
性质:一类能抑制蛋白质酪氨酸激酶活性的化合物。酪氨酸蛋白激酶能特异性地将磷酸根转移到蛋白质的酪氨酸残基上使其磷酸化,是许多配体活化的生长因子受体和一些癌基因产物,在肿瘤组织中含量高。酪氨酸蛋白激酶抑制剂可作为ATP与酪氨酸蛋白激酶结合的竞争性抑制剂,也可作为酪氨酸的类似物阻断表皮生长因子受体的肽位点和酪氨酸蛋白激酶的编码,抑制细胞增殖,可望开发为抗肿瘤药物,但对完整细胞没有表现出选择性。
CAS号:
性质:一类能抑制蛋白质酪氨酸激酶活性的化合物。酪氨酸蛋白激酶能特异性地将磷酸根转移到蛋白质的酪氨酸残基上使其磷酸化,是许多配体活化的生长因子受体和一些癌基因产物,在肿瘤组织中含量高。酪氨酸蛋白激酶抑制剂可作为ATP与酪氨酸蛋白激酶结合的竞争性抑制剂,也可作为酪氨酸的类似物阻断表皮生长因子受体的肽位点和酪氨酸蛋白激酶的编码,抑制细胞增殖,可望开发为抗肿瘤药物,但对完整细胞没有表现出选择性。
说明:补充资料仅用于学习参考,请勿用于其它任何用途。
参考词条