Expression of protease activated receptors on human lung epithelial cells;

Objective: To study the effects of PAR-2 agonists SLIGKV and tc-LIGRLO,trypsin and its inhibitors on intracellular calcium concentration [Ca~(2+)]_i in the H292 lung epithelial cell.

Objective:To study the effects of protease-activated receptor-2(PAR-2)agonists(SLIGKV and tc-LIGRLO),trypsin and its inhibitors[soybean trypsin inhibitor(SBTI)and α_1-antitrypsin(α_1-AT)]on intracellular calcium concentration([Ca~(2+)]_i)in A549 lung epithelial cell.

Regulation role of hypoxia inducible factor-1 on hypoxia induced alveolar epithelial cell apoptosis;

Effect of adenovirus ElA gene on interleukin-8 expression induced by CSE in alveolar epithelial cells;

Objective To explore the dynamic changes of expressions of surfactant protein A,B(SP-A,B)and aquaporin5(AQP5)mRNA of specificity mark in alveolar epithelial cell(AEC)of premature rats with chronic lung disease(CLD)and those significances.

Effects of cyclic mechanical stretch on the adhesion and the intracellular calcium concentration of human pulmonary epithelial cells;

Effects of mechanical strain on the proliferation of human pulmonary epithelial cells and reorganization of integrins;

In order to study the effects of mechanical strain on distribution of integrins in normal human pulmonary epithelial cell line H727, a cyclic strain unit in vitro was set up, and the redistribution of α3,α5,β1 integrin in H727 cells subjected to 24 h cyclic strain was analyzed.