Effect of selenium on expression of P38 mitogen-activated protein kinase and monocyte chemoattractant protein-1 in diabetic endothelial cells;

Objective To investigate the role of P38 mitogen-activated protein kinase (P38MAPK) for expression of VEGF in rat mesangial cells and to study the mechanism of P38MAPK on diabetic nephropathy.

Objective:To investigate the action and mechanism of p38 mitogen-activated protein kinase(p38MAPK) in up-regulating interleukin 6 expression in rat glomerular mesangial cells induced by interleukin 1β.

Wnt signal pathway and tooth development;

Transforming growth factor-beta-Smad signal pathway in the development of palate;

Study on the signal pathway of cell apoptosis in HT-29 cells and the gene expression of AQP3 induced by sodium butyrate;

The mammalian target of rapamycin, mTOR, is a serine/threonine protein kinase that plays a crucial role in the nutrient-sensitive signalling pathway and the regulation of cell growth and proliferation.

When insects are challenged by pathogenic microorganisms,signalling pathways triggered by recognition proteins of pathogen associated molecular patterns(PAMPs)induce the systemic immune re-sponse and produce respondingly innate immunity effectors such as antimicrobial peptides.

Differences of signaling pathway of lung injury between C57BL/6 and C3H/He mice exposed to fine particle;

Constitutive activation of JAK/STAT signaling pathway in leukemogenesis;

Inhibition of phospholipase C gamma1 signaling pathway promotes apoptosis of human;

Multiple kinds of MK receptors attribute to its various functions via different downstream signaling pathways.

With increasing knowledge of the inflammatory process,especially in signaling,some drugs modifying disease progress and interfering signaling pathways have been studied.

The osteogenic differentiation of mesenchymal stem cells is regulated by many signaling pathways.