Study on genic mutation types of β-thalassemia and prenatal diagnosis in Xiamen area;

A pilot study on the detection and clinical significance of PRA in children with β-thalassemia major;

Evaluation of hemoglobin agarose electrophoresis and Hb-F alkali denaturation test in diagnosis of β-Thalassemia;

Amniotic fluid gene detection in prenatal diagnosis of alpha-and beta-thalassemia;

Closely linked polymorphic marker: successful application in preimplantation genetic diagnosis for beta-thalassemia;

Identification of a Novel β Thalassemia Mutation and Development of a Method for High-throughput Mutation Detection of β-globin Gene;

Methods The reverse dot blot technique was employed in the present study for characterization of mutation in 75 fetal umbilical cord blood samples (at least one of parental affected by β thalassemia).

To investigate the structural and functional stability of an antisencse RNA expression vector in β 654 HeLa cells during the cell subculture,a vector expressing the antisense RNA which targeted against the aberrant splice sites of β thalassemia allele IVS 2 654 C→T(β 654 ) pre mRNA named pCMVA,was constructed in pcDNA3 1.

The Development in β-thalassemia for Gene Therapy;

DNA chip construction for β-thalassemia and achondroplasia;

Clinical analysis and inquire into interfere measure of 15 cases She nationality children with β-thalassemia in the east of Fujian Province.;