Objectives To elucidate the effects of 5-aminolevulinic acid-mediated photodynamic therapy(ALA-PDT)on graft-versus-host disease(GVHD)and graft-versus-leukemia(GVL)effect following allogenic bone marrow transplantation(allo-BMT)in mice with acute lymphoblast leukemia(ALL).

Among others, bone xenografting has attracted much attention from orthopaedists and has been the target toward which tremendous efforts were geared, but its clinical application remained an unsolved problem up until.

How to eliminate the antigenicity of bone xenograft while retaining its osteoinductive activities is an unsolved problem in the orthopaedic field worldwide.

Study of Immune Endurance of Speciality on Allogeneic-Bone- Marrow-Transplantation (ALLO-BMT) in Survival Mice;

Objective The study was aimed to investigate the effects of transforming growth factor beta1(TGF-β1)on acute graft-versus-host disease(aGVHD)after allogeneic bone marrow transplantation(allo-BMT).

In order to explore the influence of purified donor regulatory T cells(TReg cells)infused after allogeneic bone marrow transplantation(allo-BMT)on GVHD and hematopoietic reconstitution of mice,an allo-BMT model of C57BL/6→BALB/c mice was established.

Study on rat model of allogeneic bone marrow transplantation;

Influence of 1,25-(OH)_2D_3 and salvia miltiorrhiza on T cell subsets and immune status in rats after allogeneic bone marrow transplantation

Establishment of a mouse model of acute graft-versus-host disease after allogeneic bone marrow transplantation