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1)  collagen Ⅰ
胶原Ⅰ
1.
Objective To develop stable cultures of human endothelial cells (ECs) and smooth muscle cells (SMCs) in order to investigate the effect of ECs conditioned medium(ECCM) on proliferation and collagen Ⅰ synthesis of SMCs.
目的建立稳定的人胎盘脐带血管内皮细胞和平滑肌细胞模型来研究:内皮细胞调节的培养液对平滑肌细胞的增殖和胶原Ⅰ产物的影响。
2.
Methods By planting of complex rhBMP/fibrin and injecting bFGF into collapsed articular cartilage of rats, HE coloration and immunohistochemistry were used to observe the pathological change of injured articular cartilage and expression of collagen Ⅰ,collagen Ⅱ,then confirmed the effect of articular cartilage healing.
方法 尝试在大鼠关节内分别植入rhBMP 纤维蛋白复合物及注入bFGF ,通过HE染色法和免疫组化法观察在关节损伤处关节软骨的病理变化和胶原Ⅰ、胶原Ⅱ的表达 ,观察胫骨平台骨折后关节软骨的愈合情况。
2)  collagenⅠ
胶原Ⅰ
1.
Effects of macrophage migration inhibitory factor on collagenⅠ and Ⅲ mRNA expression in vascular smooth muscle cells in vitro;
巨噬细胞移动抑制因子对血管平滑肌细胞胶原Ⅰ、Ⅲ mRNA体外表达的影响
3)  Collagen Ⅰ
Ⅰ型胶原
1.
The Experimental Study of Shenxian Fuyuan Capsule on α-SMA and the Collagen Ⅰ Expression in 5/6 Nephrectomy Rat;
肾纤复元胶囊对5/6肾切除大鼠肾组织α-SMA和Ⅰ型胶原的影响
2.
Enhancement of AdhuVEGF_(121) gene transfection to ALP activity and collagen Ⅰ expression in femoral head of rabbits;
Ad-huVEGF_(121)基因转染对兔股骨头Ⅰ型胶原表达及ALP活性的影响
3.
The expression of collagen Ⅰ during mandibular fracture healing with the inferior alveolar nerve mutilated;
Ⅰ型胶原在去下牙槽神经支配下颌骨骨折愈合中的表达
4)  Type Ⅰ collagen
Ⅰ型胶原
1.
Preparation and test of type Ⅰ collagen-glycosaminoglycan (GAG) template;
Ⅰ型胶原-糖胺聚糖模板的制备与检测
2.
Effect of APTE modification and binding type Ⅰ collagen to TiO_2 film on the thrombus formation ability;
APTE修饰钛氧膜并固定Ⅰ型胶原对其凝血性能的影响
3.
Effects of tetramethylpyrazine on angiotensin Ⅱ-induced proliferation and type Ⅰ collagen synthesis of rat cardiac fibroblasts
川芎嗪对血管紧张素Ⅱ诱导的大鼠心肌成纤维细胞增殖及Ⅰ型胶原合成的影响
5)  collagen type Ⅰ
Ⅰ型胶原
1.
Molecular mechanism of UVB-and oxidative stress-induced collagen type Ⅰ degradation;
中波紫外线和氧化应激诱导LECs中Ⅰ型胶原降解的分子机制研究
2.
Construction of human/rat homology siRNA and its vector for collagen type Ⅰ;
人鼠同源Ⅰ型胶原siRNA及表达载体的构建
3.
A study on preparation of novel chitosan/collagen type Ⅰ scaffolds and their properties
壳聚糖/Ⅰ型胶原复合支架材料的制备及其性能的研究
6)  collagen typeⅠ
胶原Ⅰ型
补充资料:胶原三重螺旋体
分子式:
CAS号:

性质: 又称原胶原(tropocollagen)。是胶原分子的组成单元。原胶原呈细长的棒状结构,长约3000nm,直径约1.5nm,分子量为30万左右,由三条等长的α-多肽链(α链)组成。每条α链先自身左旋(螺距约0.95nm),然后相互缠绕(似电缆)形成右旋超螺旋体。螺旋体的主体部分为规整结构,其两端为伸展部分,即氨基端(5.0hm)和羧基端(7.5nm),它们又被称为肽尾(telopeptides),(图暂缺)。胶原三重螺旋体应是确指原胶原规整结构的主体部分,它们对化学试剂、酶等生物制品有很高的稳定性。

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