1) huntingtin
亨廷顿蛋白
1.
Cytoplasmic non-aggregated mutant huntingtin influencing differentiation of neural cell;
胞浆内非聚集型突变亨廷顿蛋白影响神经细胞的分化
2.
Insulin inhibition of the accumulation and toxicity of mutant huntingtin;
胰岛素抑制突变亨廷顿蛋白的聚积和毒性
3.
Huntington disease (HD) is a neurodegenerative disorder caused by an expansion of the polyglutamine tract in the N-terminal huntingtin (Htt).
亨廷顿舞蹈病(Huntington disease,HD)是由亨廷顿蛋白(huntingtin,Htt)N端多聚谷氨酰胺序列延长引起的神经退行性疾病。
3) huntingtin associated protein 1
亨廷顿蛋白相关蛋白-1
4) HAP1
亨廷顿蛋白相关蛋白1
1.
Objective This project aims to elucidate whether Huntingtin associated protein 1(HAP1) plays a role in the endocytosis and retrograde transport of BDNF and its receptors,which may offer a way to investigate the molecular biology mechanism of Huntington disease.
目的拟探讨亨廷顿蛋白相关蛋白1(HAP1)与脑源性神经营养因子(BDNF)及其受体p75NTR的胞吞和逆向囊泡运输关系,深入阐述亨廷顿舞蹈病的分子生物学机制。
5) Huntington disease
亨廷顿病
1.
We report here a simple and effective method to assess the CAG repeat size of HD gene for gene diagnosis of Huntington disease,Genomic DNA sequences in polymorphic CAG repeat HD gene was amplified by PCR with TaKaRa LA Taq DNA polymerase and GC buffer.
为了简单高效检测HD基因开放阅读框5'端(CAG)n三核苷酸重复序列,建立快速准确的亨廷顿病(Hun-tington disease,HD)基因诊断方法,应用TaKaRa LATaqDNA聚合酶配合GC buffer扩增HD基因包含(CAG)n重复序列的目的片段,非变性聚丙烯酰胺凝胶电泳检测后回收(CAG)n拷贝数异常增多的目的片段,再次PCR扩增后将产物连接至T载体,进行DNA测序确定CAG的拷贝数。
2.
Using the molecular biological technology,we established the molecular diagnostic methods for Wilson’s disease, Huntington disease and spinocerebellar ataxias.
亨廷顿病(Huntington disease,HD)是一种呈常染色体显性遗传的中枢神经系统退行性病变,临床表现主要为进行性的运动障碍、精神异常和智能衰退。
6) Huntington's disease
亨廷顿病
1.
Impaired function of pancreatic β cells in the R6/2 transgenic mouse model of Huntington's disease
R6/2型亨廷顿病转基因小鼠胰岛β细胞功能损伤
补充资料：许佐廷
许佐廷 许佐廷 清代医家。字乐泉，安徽歙县人。自幼习儒，其同邑有郑麈者，精喉科，颇有起死回生之术，人称“医仙”，佐廷获其著作，并加以增订，名《喉科秘钥》，刊刻于世。晚年又撰《喉科白腐要旨》，认为此证宜清润养阴，从肺肾而治。尚有与其侄合著之《活幼珠玑》一书，均有刊本行世。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条