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1)  FK506 inhibition
FK506阻断
2)  Tacrolimus
FK506
1.
Central nervous system toxicity induced by tacrolimus after renal transplantation;
肾移植术后应用FK506的神经毒性作用
2.
Inhibitive effect of low-dose Tacrolimus on expression of inducible nitric oxide synthase and neuronal apoptosis in rats following contusion spinal cord injury;
脊髓冲击伤后应用低剂量FK506抑制iNOS表达及神经细胞凋亡
3.
The present study was aimed to evaluate whether the interindividual variation of tacrolimus dosage.
目的探讨肝移植术后口服免疫抑制剂FK506的剂量及其全血谷浓度的个体差异与供体的肝药酶P450 3A5(CYP3A5)基因多态性的关系。
3)  disconnecting [英][,diskə'nekt]  [美][,dɪskə'nɛkt]
阻断
1.
Disconnecting Nitrosodimethylamin Compost by Extract of Ligustrum Lucidum Ait;
女真子提取物对N-亚硝胺合成阻断的研究
2.
The capability of scavenging sodium nitrite and disconnecting nitrosamine synthesis with hawthorn extracts by microwave method were determined by spectrophotometry under simulated human gastric juice,and was compared with vitamin C.
通过微波法提取山楂的活性成分,在模拟人体胃液条件下,采用分光光度法测定了不同浓度的山楂提取液对亚硝酸钠的清除能力和对亚硝胺合成的阻断能力,并与Vc进行了比较。
3.
This paper deals with the capabilities of extracts from different parts of corn in disconnecting nitrosodimethylamin(NDMA) compost and scavenging sodium nitrite.
研究在体外模拟胃液条件下 ,玉米各部位提取物对亚硝酸胺合成的阻断作用和对亚硝酸盐的清除作用。
4)  block [英][blɔk]  [美][blɑk]
阻断
1.
The study of Uterine Blood Temporary Block and Partial Reduction in the Treatment of Postpartum Hemorrhage;
子宫血流暂时阻断加子宫局部血流缩减术在产后出血中的应用研究
2.
Application of block and angioplasty of pulmonary vessel in no-bleeding lung resection;
肺血管阻断和成形技术在无出血肺切除术中的应用
3.
Effect on Blood Vessels of Temporary Block of Goat Abdominal Aorta;
羊腹主动脉暂时阻断对血管的影响
5)  Occlusion [英][ɔ'klu:ʒən]  [美][ə'kluʒən]
阻断
1.
An Experimental Study on Ischemic Injuries of Cervical Spinal Cord after Acute Occlusion of Anterior Spinal Artery;
急性脊髓前动脉阻断致颈髓缺血损伤的实验研究
2.
Applying of Modified Pringle s Hepatic Vascular Occlusion for Resection of Liver Cancer;
改良Pringle肝血流阻断法在肝癌切除术中的应用
3.
Objective In order to invetigate the difference in the detection between symptomatic and asymptomatic patients with unilateral carotid artery occlusion transcranial doppler ultrasound.
目的 研究经颅多普勒(TCD)在单侧颈动脉阻断试验(CAO)中应用的价值。
6)  Interruption [英][,ɪntə'rʌpʃn]  [美]['ɪntə'rʌpʃən]
阻断
1.
Research Progress in High Risk Factors of HBV Intrauterine Infection and Interruption of Mother-to-Infant Transmission;
乙型肝炎病毒宫内感染的高危因素及母婴传播阻断措施的研究进展
2.
The Interruption of TNF Monoclonal Antibody on Muscular Protein Hypercatabolism after Scalding in Rat;
TNF单抗阻断烫伤大鼠蛋白质高分解代谢的实验研究
3.
Sniffer and Interruption of TCP/IP Communication;
TCP/IP通信的监听与阻断
补充资料:FK-506
分子式:
CAS号:

性质:筑波链霉菌Strep tomyces tsukubaensis产生的23元环的大环内酯族的免疫抑制剂。熔点127~129℃,旋光度-84.4°(c=1.02,三氯甲烷)。柱状结晶,具有高度脂溶性,极低水溶性。抑制抗体的产生和移植物的排斥作用及白细胞介素IL-2、IL-3和干扰素IFN-r的产生。体内的免疫抑制作用比环孢素强数倍,体外试验强100倍。用于心脏、肺脏移植有很好效果。肾脏移植效果较环孢素差,肾毒性比环孢素大。本品对某些曲菌和镰刀菌有抗真菌作用。

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