1)  coactivator
辅激活蛋白
1.
To further understand the detailed molecular mechanism of transcription regulation controlled by estrogen receptor related receptor α1(ERRα1) in breast cancer and to identify coactivators interacting with ERRα1 , human mammary gland tissue cDNA library was screened with ligand binding domain (LBD) of ERRα1 as the bait by yeast two-hybrid system.
为深入研究乳腺癌中孤儿受体ERRα1参与基因表达调控的详细机理,特别是核受体辅激活蛋白在其中的作用,以ERRα1的LBD为诱饵,用酵母双杂交系统筛选人乳腺组织cDNA文库得到了与其有明显相互作用的快速骨骼肌型肌钙蛋白I(TNNI2)。
2)  nuclear receptor co-activator 1 gene(NCOAl)
核受体辅激活蛋白1基因（NCOA1）
3)  coactivator
辅激活因子
1.
CREB binding protein (CBP) is a crucial transcriptional coactivator, which contains highly conserved sequence and can interact with about 300 kinds of transcription factors, and is considered to be the key point of the regulation of mammalian genes transcription.
CREB结合蛋白(cAMPresponseelementbindingproteinbindingprotein,CBP)是一种重要的转录辅激活因子,具有高度保守的序列,能够与300多种转录因子相结合,被认为是哺乳动物基因转录调控中的关键位点。
2.
Peroxisome proliferators-activated receptor-γ coactivator-1 (PGC-1) is a versatile transcriptional regulator.
过氧化物酶体增殖物激活受体γ辅激活因子1(peroxisomeproliferatoractivatedreceptorγcoactivator1,PGC1)是一种多功能的转录调节因子,其广泛参与线粒体生物合成及能量代谢、糖脂代谢等多条代谢通路调节的特点预示PGC1在现代医学中可能极具应用潜力。
3.
Peroxisome proliferators-activated receptor-γ coactivator-1 is broadly involved in several key cellular pathways including mitochondrial biogenesis, hepatic gluconeogenesis via interacting with many transcription factors, which is highly valuable to maintain the energy balance of organisms.
过氧化物酶体增殖物激活受体γ辅激活因子 1(peroxisome proliferator activated receptor γcoactivator 1,PGC 1)通过结合下游转录因子广泛参与线粒体生物合成、肝糖异生等重要代谢通路调节,对于维持生物体能量动态平衡有重要生理意义。
4)  Transcriptional coactivator
转录辅激活子
1.
It has been demonstrated that transcriptional coactivator has close relationship with transcriptional factors and can enhance the co.
现有研究证明,与转录因子活力有关联的是转录辅激活子,它能增强转录因子和顺式作用元件的结合。
5)  Transcriptional coactivator(TC)
转录辅激活因子（TC）基因
6)  Transcriptional coactivator
转录辅激活因子基因
参考词条
补充资料：钙离子激活的中性蛋白酶
分子式：
CAS号：

性质：又称钙依蛋白酶(calcium-dependent protease；calpains)。广泛而大量地存在于脊椎动物的各种组织和细胞中。是一种典型的半胱氨酸蛋白酶，其活性绝对需要钙离子，在中性pH值，并有还原剂(如DTT)存在的条件下，其活性最高；而在巯基修饰剂和钙离子螯合剂(如EDTA)存在时，活性降低或丧失。其功能涉及蛋白激酶C的活化，细胞骨架蛋白的水解，其他蛋白激酶的磷酸化，微管蛋白的聚合和解集等。

说明：补充资料仅用于学习参考，请勿用于其它任何用途。