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1)  antitumor effect
抗瘤作用
1.
Investigation of antitumor effect of natural radix arnebiae seu Lithospermi naphthoquinone compounds and its derivatives;
天然紫草萘醌类化合物及其衍生物的抗瘤作用研究
2.
Studies on antitumor effects and acute toxicity of anuoning emulsion;
阿诺宁乳化剂的抗瘤作用和急性毒性试验
3.
The cytotoxic effect and antitumor effect of paclitaxel liposome were studied by using MTT assay method in vitro and in vivo antitumor test.
为研究紫杉醇脂质体的体外细胞毒作用及体内抗瘤作用
2)  anti-tumor effect
抗肿瘤作用
1.
Study on anti-tumor effects of Auricularia auriculajudae polysaccharide;
黑木耳多糖抗肿瘤作用的研究
2.
Study on comparison on anti-tumor effects of three kinds of aloe polysaccharide;
3种芦荟多糖抗肿瘤作用的比较分析
3.
Progress in the study on anti-tumor effect of seaweed polysac- charides;
海藻多糖抗肿瘤作用的研究进展
3)  antitumor [英]['ænti'tjumə]  [美][,æntɪ'tumɚ, -'tju-]
抗肿瘤作用
1.
Review on the Antitumor Effect of the Active Substances from Earthworm;
蚯蚓活性成分的抗肿瘤作用
2.
A preliminary research on the antitumor effect of β-carotene and lycopene in vitro;
β-胡萝卜素与番茄红素体外抗肿瘤作用研究
3.
The study of the antitumor effect of doxifluridine lyophilized powder for injection;
脱氧氟尿苷冻干粉针剂的抗肿瘤作用研究
4)  antitumor effect
抗肿瘤作用
1.
Study on in vitro cytotoxicity and in vivo antitumor effect of liposomes containing topotecan hydrochloride;
盐酸拓扑替康脂质体的体外细胞毒及体内抗肿瘤作用
2.
An experiment study on antitumor effect of Haishengsu injection;
海生素注射液抗肿瘤作用的实验研究
3.
Extraction and measurement of two kinds of seaweed polysaccharides and their antitumor effect in vitro;
两种海藻多糖的提取分析及其体外抗肿瘤作用
5)  Antitumor activity
抗肿瘤作用
1.
Advances in antitumor activity of Scorpion;
蝎及蝎毒抗肿瘤作用研究进展
2.
Correlation between antitumor activity of berberine and the inhibition of Wnt/β-catenin signal pathway;
小檗碱抗肿瘤作用与Wnt/-βcaten in信号转导关系
3.
Methods The antitumor activity against human malignant melanoma A375 ,human cutaneous T-cell lymphoma Hut-78 and human epidermal cancer A431 cell lines were determined by MTT assay in vitro.
方法用A375黑色素瘤细胞、Hut-78人皮肤T细胞淋巴瘤细胞和A431人表皮癌细胞为癌细胞株,观察茅莓总皂苷的体外抗肿瘤作用。
6)  anti-tumor activity
抗肿瘤作用
1.
Comparison of anti-tumor activity induced by dendritic cells from human peripheral blood and cord blood cultured in vitro;
人外周血及脐血树突状细胞的体外诱导及抗肿瘤作用比较
2.
Isolation and purification of lily polysaccharide and its anti-tumor activity
百合多糖的分离纯化及抗肿瘤作用
3.
To investigate the anti-tumor activity of daphnoretin in vitro,daphnoretin was obtained from Wikstroemia indica by means of extracting with alcohol,separating with silica gel and recrystallizing.
研究西瑞香素(daphnoretin)的体外抗肿瘤作用。
补充资料:抗黑瘤
分子式:C6H10N6O
分子量:182.18
CAS号:4342-03-4

性质:微黄色结晶或粉末。熔点205℃,也有报道250-255℃(分解)。易溶于酸,微溶于甲醇,乙醇,不溶于水。遇热分解,对酸和光不稳定。

制备方法:以氰乙酸乙酯为原料,经加成、胺化、重氮化、偶合、还原、甲酰化、环合、中和、重氮化、缩合,经过中间体β-亚胺基-β-乙氧基丙酸乙酯盐酸盐,α-脒基乙酰胺盐酸盐,α-脒基-α-苯偶氮基乙酰胺盐酸盐,5-氨基咪唑-4-羧酰胺盐酸盐而得。

用途:抗肿瘤药。临床上用于恶性黑色素瘤,约20-30%有效,与长春醛碱和卡氮芥合并应用,可提高疗效。此外对肺鳞癌、肉瘤、平滑肌肉瘤、纤维肉瘤亦有一定疗效。对消化道癌的疗效不佳。

说明:补充资料仅用于学习参考,请勿用于其它任何用途。
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