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1)  ~(99)Tc~m-MIBI
99Tcm-MIBI
1.
Pharmacological experiment of ~(99)Tc~m-MIBI and ~(99)Tc~m-CO-MIBI are performed by self-contrast in dogs.
以犬为实验动物,99Tcm-CO-MIBI和99Tcm-MIBI为显像剂,采用自身对照的方法,通过采集血样、采集动态图像和全身显像获得药物在犬体内的代谢动力学参数、生物分布、靶与非靶放射性摄取比和全身、心脏平面及断层影像等药效学结果。
2.
The correlation between the uptake of ~(99)Tc~m-MIBI and the expression of P-glycoprotein (Pgp) in patients with lung malignant tumor is explored by γ-detecting probe (GDP) intraoperatively.
99Tcm-MIBI术中γ探测法探讨活体肺部恶性肿瘤组织对99Tcm-MIBI的摄取和肿瘤细胞P-糖蛋白(Pgp)表达间的关系。
3.
SPECT scintigraphy is used in 62 patients with medullary thyroid carcinoma(MTC), which are divided into two groups: 32 patients by ~(99)Tc~m (V)-DMSA and 30 patients by ~(99)Tc~m-MIBI.
对62例甲状腺髓样癌(MTC)患者手术前行SPECT亲肿瘤显像,其中99Tcm(V)-DMSA显像组32例,99Tcm-MIBI显像组30例;并对两组患者早期和延迟影像的定性和半定量分析结果进行比较。
2)  Tc m MIBI
99Tcm-MIBI
1.
The clinical values of tumors positive imaging with 99 Tc m MIBI is evaluated.
静脉注射 99Tcm-MIBI15~ 30 min后 ,用美国 GE公司 SPX- 6型 SPECT行病变局部平面和断层显像 ,计算肿瘤与本底比值 (T/ B) ,当 T/ B≥ 1。
3)  ~(99)Tc~m-CO-MIBI
99Tcm-CO-MIBI
1.
Pharmacological experiment of ~(99)Tc~m-MIBI and ~(99)Tc~m-CO-MIBI are performed by self-contrast in dogs.
以犬为实验动物,99Tcm-CO-MIBI和99Tcm-MIBI为显像剂,采用自身对照的方法,通过采集血样、采集动态图像和全身显像获得药物在犬体内的代谢动力学参数、生物分布、靶与非靶放射性摄取比和全身、心脏平面及断层影像等药效学结果。
4)  ~(99)Tc~(m)
99Tcm
1.
A new imaging agent for β-amyloid plaques,~(99)Tc~(m)-MAMA-DMABP was prepared,and its biodistribution in normal mice was studied.
制备了新的Aβ斑块显像剂99Tcm-酰胺基氨基二硫醇(MAMA)-4-氨基-4′-二甲氨基联苯(DMABP),并研究了其在正常小鼠体内的生物分布。
2.
In order to investigate in vivo absorption and distribution of gelatin after injection intravenously,gelatin was directly labeled with reduced ~(99)Tc~(m) that was formed by reduction of ~(99)Tc~(m)O~-_(4) with NaBH_(4).
为考察明胶静脉注射后在机体内的吸收及分布情况,用99Tcm对明胶进行整体标记,然后将标记物99Tcm-明胶静脉注射于小鼠和家兔体内,检测不同时间后标记物的生物分布。
5)  ~(99)Tc~m
99Tcm
1.
Ciprofloxacin(CPF) made in China is labeled with ~(99)Tc~m and the factors which affects the labeling efficiency are determined.
确定了99Tcm-环丙沙星(ciprofloxacin,CPF)的最佳标记条件,在此基础上制备了环丙沙星冻干品药盒,并初步观察了99Tcm-CPF在炎症模型小鼠体内的分布。
2.
~(99)Tc~m-HYNIC-Annexin Ⅴ has been successfully evaluated in animal models and the results show that the cell apoptosis can be assaied by which.
结果表明:每个AnnexinⅤ的蛋白分子能偶连2个HYNIC,标记率为98%,标记物的放化纯度在6 h后仍然>95%;99Tcm-HYNIC-AnnexinⅤ在动物模型中能有效检测细胞凋亡。
3.
The complexes ~(99)Tc~mN-DMCHI and ~(99)Tc~m-DMCHI are prepared by ligand exchange reaction and directly labeling method,respectively.
分别通过配体交换法和直接标记法制备得到放化纯大于95%的脂溶性配合物99TcmN DMCHI和99Tcm DMCHI,二者在室温下均可稳定6h以上。
6)  99 Tc m
99Tcm
1.
AIM: To explore the method of 99 Tc m direct labeling of angiostatin (AS) and to investigate the stability and biological activity of 99 Tc m AS in vitro .
目的 :探索用99Tcm 直接标记血管抑素 (angiostatin ,AS)的方法 ,并研究标记产物的体外稳定性及其生物活性 。
2.
Based on the labeling c myc mRNA oligonucleotide with 99 Tc m, the labeling compounds are entrapped with liposome.
在 99Tcm 标记 DNA的基础上 ,采用阳离子脂质体对其进行包裹 ,获得了脂质体介导的 99Tcm-DNA。
3.
Objective To label monoclonal antibodies (McAb) with 99 Tc m via 2-IT.
目的 研究 2 -IT法99Tcm 间接标记单克隆抗体。
补充资料:technetium 99Tcm 2-methoxy isobutylisonitrile[MIBI]injection
分子式:
CAS号:

性质:99Tcm-MIBI  injec-tion  99Tem-MIBI是带+1电荷的六异腈络合物,即99Tcm[BIMI]6+1。99Tcm-MIBI注射液是放射性诊断用药,用作心肌灌注显像剂,可测定运动和静态时的心肌灌注情况,诊断心肌梗死和一过性心肌缺血。

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