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1)  cytochrome P450 3A4
细胞色素P450 3A4
1.
Association between cytochrome P450 3A4 gene 894C>T single nucleotide polymorphism and clopidogrel resistance;
细胞色素P450 3A4 894C>T位点基因多态性与氯吡格雷抵抗的关系
2.
Human cytochrome P450 3A4 plays a dominant role in the metabolic of endogenous and exogenous compounds.
细胞色素P450 3A4在许多内源性及外源性化合物的氧化及还原代谢 中起关键作用,对CYP3A4基因表达的研究具有重要意义。
3.
P-glycoprotein (P-gp) and cytochrome P450 3A4 (P450 3A4) enzyme have become the two main ADME targets because of their special physiological fu.
P-glycoprotein (P-gp)和细胞色素P450 3A4酶(P450 3A4)分别是人体对药物分子产生生物物理和化学作用的代表性靶蛋白。
2)  CYP3A4
细胞色素P450酶3A4
1.
METHODS:The mechanisms for Chinese materia medica and its chemical compositions to change the bioavailability of orally taken substrates by its inhibiting or inducing intestinal CYP3A4 and P-gp were summarized,and which were analyzed by combining the literature.
方法:归纳中药或中药化学成分对肠道细胞色素P450酶3A4(CYP3A4)及P-糖蛋白(P-gp)的抑制或诱导作用而改变口服底物药物生物利用度参数的机制,并结合文献资料分析说明。
3)  CytochromeP450 isoenzyme 3A4
细胞色素P450同功酶3A4
4)  cytochrome P450
细胞色素P450
1.
Studies on the relationship of cytochrome P450 and selective toxicity of Celangulin Ⅴ against insect;
细胞色素P450酶系与苦皮藤素Ⅴ对昆虫选择毒性的关系研究
2.
The research progress of plant cytochrome P450 enzymes and their relationship with xenobiotics;
植物细胞色素P450酶系的研究进展及其与外来物质的关系
3.
Quantiative Structure-Activity Relationship Between p-Aminobenzoates and Formation Rate of Cytochrome P450 Metabolic Intermediate Complex;
对氨基苯甲酸酯同系物与细胞色素P450代谢中间体络合物形成速率的定量构效关系
5)  cytochromes P450
细胞色素P450
1.
Effects of gatifloxacin and ciprofloxacin on hepatic cytochromes P450 in rats;
加替沙星和环丙沙星对大鼠肝细胞色素P450酶系的影响
2.
Role of Cytochromes P450 Expression in Plant Defence Responding to Pathogens;
细胞色素P450表达在植物防御反应中的作用
3.
Objective: To study the relationship between genetic polymorphism of cytochromes P4502E1 RsaⅠand smoking,alcohol drinking habit with the susceptibility of rectal cancer.
目的:研究细胞色素P4502E1(CYP2E1)基因RsaⅠ多态性、烟酒习惯与直肠癌遗产易感性的关系。
6)  CYP450
细胞色素P450
1.
Preparation and Preliminary Identification of HLM and CYP450 Monoclonal Antibody;
单株抗人肝脏微粒体蛋白及细胞色素P450单克隆抗体的制备及初步鉴定
2.
Advance in search for influence of CYP450 genetic polymorphism to drug metabolism;
细胞色素P450氧化酶基因多态性对药物代谢影响的研究进展
3.
CYP450 and Its Application in the Study on New Drug Metabolism and Development;
细胞色素P450酶在药物代谢及开发研究中的应用
补充资料:细胞色素P-450
分子式:
CAS号:

性质:为一种血红素蛋白,它是一个末端氧化酶,由于当它处于还原形式时,与一氧化碳结合形成一种亚铁羰基加成物。在可见光450nm处有最大的吸收峰,故命名为细胞色素P-450,和其他的天然血红素相同,分子中的铁原子是以与原卟啉IX呈符合物的形式存在,肝中含细胞色素P-450酶较丰富。

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