3) myeloproliferative disorders
骨髓增殖性疾病
1.
Objective: Our purpose was to investigate if there are spontaneous megakaryocyte growth in liquid culture in vitro in patients with myeloproliferative disorders (MPD) who had spontaneous megakaryocyte colony (CFU MK) formation.
目的 :观察有自发性巨核细胞集落 (CFU MK)形成的骨髓增殖性疾病 (MPD)患者 ,其液体培养是否也有自发性巨核细胞生长。
2.
Objective:To detect the JAK2V617F mutation in myeloproliferative disorders (MPD)by allele-specific primer polymerase chain reaction and evaluate the significance of JAK2V617F in diagnosis and therapy of MPD.
目的:对bcr/abl融合基因阴性的骨髓增殖性疾病(myeloproliferativedisorders,MPD)病人进行JAK2V617F点突变定性检测,探讨bcr/abl融合基因阴性MPD的主要分子致病机制和诊断指标,为临床诊断、治疗提供理论依据。
3.
Objective:To detect the JAK2V617F mutation in myeloproliferative disorders(MPD) of Qinghai province by allele-specific primer polymerase chain reaction and evaluate the significance of JAK2V617F in diagnosis and therapy of MPD.
目的:对青海省bcr/abl融合基因阴性的骨髓增殖性疾病(myeloproliferativedisorders,MPD)病人进行JAK2V617F点突变定性检测,分析JAK2V617F点突变在我国西部地区MPD病人中的表达率,为临床诊断、治疗提供理论依据。
4) MPD
骨髓增殖性疾病
1.
The discovery of JAK2V617F point mutation is an important breakthrough for understanding of molecular mechanism of BCR-ABL negative MPD,especially PV.
骨髓增殖性疾病(MPD)中除慢性粒细胞性白血病(CML)发病机制已明确外,真性红细胞增多症(PV),原发性血小板增多症(ET),原发性骨髓纤维化(IMF)等BCR-ABL阴性的MPD均尚不明确。
2.
Objective: Myeloproliferative disorders (MPD) are clonal disorders characterized by excess proliferation of cells from one or more myeloid lineages.
目的:骨髓增殖性疾病(myeloproliferative disorders,MPD)是骨髓细胞克隆性或肿瘤性增殖的疾病,包括属于慢性骨髓增殖性疾病(CMPD)范畴的慢性粒细胞白血病(CML)、真性红细胞增多症(PV)、原发性血小板增多症(ET)、慢性特发性骨髓纤维化症(CIMF)、慢性中性粒细胞白血病(CNL)及慢性嗜酸性粒细胞白血病(CEL)和属于骨髓增生异常/骨髓增殖性疾病(MDS/MPD)范畴的不典型慢粒(aCML)、慢性粒-单核细胞白血病(CMML)及幼年型粒。
5) Myeloproliferative disease
骨髓增殖性疾病
1.
Objective:To observe the therapeutic effect of integrated traditional Chinese and Western medicine treatment on atheroangitis diseases caused by myeloproliferative diseases Methods:Twenty five patients were treated by integrated traditional Chinese and western medicine for 2 to 3 courses.
目的 :观察骨髓增殖性疾病 (myeloproliferativediseases ,MPD)所致动脉栓塞性疾病 (atheroangitisdiseases,AAD)的中西医结合治疗效果。
2.
In order to investigate the frequency of MPLW515L and JAK2V617F point mutations of the patients with myeloproliferative disease(MPD) in Nanjing area,MPLW515L and JAK2V617F point mutations were simultaneously detected by alleles specific polymerase chain reaction(AS-PCR) and sequencing in 190 MPD patients.
为了探讨MPLW515L和JAK2V617F点突变在南京地区骨髓增殖性疾病(MPD)中的突变情况,采用等位基因特异性聚合酶链反应(AS-PCR)及基因测序方法检测190例MPD患者的MPLW515L和JAK2V617F点突变。
3.
Chronic myeloproliferative disease (CMPD) is a group of malignant blood disorders including polycythemia vera,essential thrombocythemia,primary myelofibrosis,chronic myeloid leukemia,and so on.
慢性骨髓增殖性疾病(chronic myeloproliferative disease CMPD)是一组骨髓增殖性的恶性肿瘤,包括真性红细胞增多症,原发性血小板增多症,原发性骨髓纤维化和慢性髓系白血病等,其特征是一系或多系造血细胞的异常增生。
6) Myeloproliferative disorder
骨髓增殖性疾病
1.
JAK2 V617F mutation in BCR-ABL negative patients with myeloproliferative disorder and its clinic significance
BCR-ABL阴性骨髓增殖性疾病患者JAK2 V617F突变的检测及其临床意义
2.
The key molecular events in the pathogenesis of myeloproliferative disorders(MPD) have been poorly defined to date,except the case of chronic myeloid leukaemia with the associated rearranged gene bcr/abl.
骨髓增殖性疾病(myeloproliferative disorders,MPD)中已明确bcr-abl是慢性粒细胞白血病发病的关键环节,但bcr-abl阴性MPD发病的分子机制研究进展缓慢。
补充资料：白血病性骨髓组织增生
白血病性骨髓组织增生
leukemic myelosis
由于某些疾病引起与白血病相似的骨髓象改变，见于某些严重感染。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条