1) κ-opioid receptor
κ-阿片受体
1.
Effects of κ-opioid receptor agonist U50488H on the coronary microcirculation and ventricular arrhythmias during myocardial ischemia and reperfusion in rats;
κ-阿片受体激动剂U50488H对缺血/再灌注损伤大鼠冠状微循环和室性心律失常的影响
2.
Direct protectory effects of κ-opioid receptor agonist U50488H on myocardial ischemia-reperfusion in rats
κ-阿片受体激动剂U50488H对大鼠心肌缺血再灌注损伤的直接保护作用
3.
Aim: To determine whether activation of κ-opioid receptor with U50,4 88 H, a selective κ-opioid receptor agonist, produces any changes in electrical u ncoupling during prolonged ischemia and whether these changes in electrical unco upling is associated with the cardioprotection induced by κ-opioid receptor ac tivation, and to explore the possible mechanism.
目的:研究κ-阿片受体兴奋诱导的心肌保护作用是否与其对心肌缺血期间电耦联的影响有关,并探讨这种作用的可能机理。
2) κ-opioid receptor
κ阿片受体
1.
Antiarrhythmic effect and underlying mechanism of κ-opioid receptor in rats with myocardial ischemia and reperfusion;
κ阿片受体在抗缺血/再灌注大鼠心律失常中的作用机制
2.
Mediative effect of κ-opioid receptor on blood pressure in the rats;
κ阿片受体介导的降血压作用
3.
Diuretic mechanism of κ-opioid receptor agonist U50,488H;
κ阿片受体激动剂U50,488H的利尿作用机制
3) U50488H
κ阿片受体激动剂
1.
AIM To study the effects of U50488H on the contents of NO, ET and Ang Ⅱ in HPH rats and to explore the mechanisms underlying the preventive and therapeutic effects of U50488H on hypoxic pulmonary hypertension (HPH).
目的研究κ阿片受体激动剂(U50488H)对低氧性肺动脉高压(HPH)大鼠体内一氧化氮(NO)、内皮素(ET)及血管紧张素Ⅱ(Ang Ⅱ)等血管活性物质水平的影响,初步探讨其防治HPH的作用机制。
4) κ-opioid receptor agonist
κ-阿片受体激动剂
1.
The purpose of this animal research to investigate the effects of combinedα_2-adrenergic receptor agonist andκ-opioid receptor agonist on cardiac function in rabbits,and to explore if they can improve postresuscitation myocardial dysfunction.
本研究观察联合应用选择性α_2-肾上腺素能受体激动剂米伐西醇(mivazerol)和κ-阿片受体激动剂U50488H对兔心肺复苏后心脏功能的影响,明确两者联用是否减轻复苏后心肌损伤,改善复苏后心功能不全。
5) U50,488H
选择性κ阿片受体激动剂
1.
AIM: To investigate the relaxant effect of U50,488H (a selective κ-opioid receptor agonist) on renal artery in rats and the underlying mechanism.
目的 :观察U5 0 ,4 88H(选择性κ阿片受体激动剂 )对大鼠肾动脉的舒张作用 ,并探讨其机制 。
6) κ opioid
κ-阿片
1.
AIM and METHODS: To investigate the effects of U50,488H (a selective κ opioid receptor agonist) on cardiac hypertrophy and cardiac cells growth induced by catecholamine.
目的与方法 :在儿茶酚胺诱导的大鼠心肌肥厚及培养的心肌细胞中 ,观察 κ-阿片受体选择性激动剂 U5 0 ,4 88H对心肌肥厚及心肌细胞生长的作用。
补充资料：阿片受体
分子式：
CAS号：
性质：为介导阿片类镇痛药及内源性阿片肽作用的受体。药理学实验已证明至少存在着μ、K、δ三种阿片受体，属于G蛋白偶联受体；并认为每种阿片受体仍具有多个亚型。目前已知μ、K、δ受体均可介导镇痛。
CAS号：
性质：为介导阿片类镇痛药及内源性阿片肽作用的受体。药理学实验已证明至少存在着μ、K、δ三种阿片受体，属于G蛋白偶联受体；并认为每种阿片受体仍具有多个亚型。目前已知μ、K、δ受体均可介导镇痛。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条