1) rosuvastatin
罗伐他汀
1.
A new HMG-COA reductase inhibitor:rosuvastatin;
新型HMG-CoA还原酶抑制剂罗伐他汀
2.
t-Butyl(3R,5S)-6-oxo-3,5-O-isopropylidene-3,5-dihydroxyhexanoate,a key intermediate of rosuvastatin, was synthesized from L-(-)malic acid by esterification,reduction,hydroxyl protection,condensation,carbonyl group reduction,hydroxyl protection,deprotection and Swern oxidation with an overall yield of 25%.
L-(一)-苹果酸经酯化、还原、羟基保护、缩合、羰基还原、羟基保护、脱硅保护和Swern氧化等反应制得罗伐他汀的关键中间体(3R,5S)-6-氧代-3,5-O-亚异丙基-3,5-二羟基己酸叔丁酯,总收率25%。
3.
The pharmacology, pharmacokinetic and clinical evaluation of rosuvastatin are reviewed.
罗伐他汀是一种全合成的具有高度肝选择性的新甲基羟戌二酰辅酶(HMG-CoA)还原酶抑制药。
2) Rosuvastatin
罗苏伐他汀
3) lovastatin
[英]['ləuvə,stætin] [美]['lovə,stætn]
洛伐他汀
1.
Advances on lovastatin fermentation by Aspergillus terrus;
土曲霉洛伐他汀发酵的研究进展
2.
Advances in the Studies of Lovastatin Biosynthesis and Its Related Genes;
洛伐他汀生物合成及其相关基因研究进展
3.
Preliminary studies on conditions for microbial conversion of lovastatin;
微生物转化洛伐他汀条件的初步研究
4) pitavastatin
匹伐他汀
1.
Improvement in synthesis of the intermediate of pitavastatin;
匹伐他汀中间体的合成工艺改进
2.
Determination of pitavastatin in human plasma by liquid chromatographytandem mass spectrometry;
液相色谱-串联质谱法测定人血浆中匹伐他汀
3.
Effect of different dosages of pitavastatin on blood flow recovery in ischemic limbs of mice;
不同剂量匹伐他汀对小鼠缺血肢血流恢复的影响
5) mevastatin
美伐他汀
1.
Study on Microbial Transformation of Mevastatin to Pravastatin;
微生物转化美伐他汀为普伐他汀的研究
2.
Mevastatin induces apoptosis of human non small cell lung carcinoma and its molecular mechanism;
美伐他汀诱导人非小细胞肺癌细胞凋亡及其分子机制的研究
3.
Role of P21 protein and survivin on apoptosis-inducing effect by mevastatin against NSCLC cells;
P21蛋白和生存素在美伐他汀诱导人非小细胞肺癌凋亡中的作用
6) simvastatin
辛伐他汀
1.
Improved synthesis of simvastatin;
辛伐他汀的合成工艺改进
2.
Preparation of sustained-release dropping pills of simvastatin and its dissolution rate;
辛伐他汀缓释滴丸的制备及体外释放度考察
补充资料：罗伐他汀
分子式：C22H28FN3O6S
分子量：481.54
CAS号：287714-41-4
性质：
分子量：481.54
CAS号：287714-41-4
性质：
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条