1) U50488H
U50488H
1.
COX-2 mediates U50488H-induced delayed cardioprotection in isolated rat heart;
COX-2参与U50488H诱导的延迟性心肌保护作用
2.
Direct protectory effects of U50488H on myocardial ischemia and reperfusion in rats;
U50488H对缺血-再灌注大鼠心肌的直接保护作用
3.
Effects of U50488H on ventricular arrhythmias induced by myocardial ischemia and reperfusion in rats;
к阿片受体激动剂U50488H对大鼠心肌缺血再灌注室性心律失常的影响
2) U50488H
κ阿片受体激动剂
1.
AIM To study the effects of U50488H on the contents of NO, ET and Ang Ⅱ in HPH rats and to explore the mechanisms underlying the preventive and therapeutic effects of U50488H on hypoxic pulmonary hypertension (HPH).
目的研究κ阿片受体激动剂(U50488H)对低氧性肺动脉高压(HPH)大鼠体内一氧化氮(NO)、内皮素(ET)及血管紧张素Ⅱ(Ang Ⅱ)等血管活性物质水平的影响,初步探讨其防治HPH的作用机制。
3) U50488
US50488
4) U50,488H
U50,488H
1.
Effects of U50,488H on potassium current in ventricular myocytes of normal and hypoxic rats;
U50,488H对正常及缺氧心肌细胞钾电流的作用
2.
Anti-arrhythmic effects of U50,488H involving the inhibition of Na~+ current in ischemia/reperfusion rat heart;
U50,488H抗大鼠缺血/再灌注损伤心律失常作用与抑制钠通道电流有关
3.
Vasorelaxing effect of U50,488H on pulmonary artery in rats and underlying mechanism;
U50,488H对大鼠肺动脉的舒张作用及机制
5) U50,488H
选择性к阿片受体激动剂
6) U50,488H
选择性κ阿片受体激动剂
1.
AIM: To investigate the relaxant effect of U50,488H (a selective κ-opioid receptor agonist) on renal artery in rats and the underlying mechanism.
目的 :观察U5 0 ,4 88H(选择性κ阿片受体激动剂 )对大鼠肾动脉的舒张作用 ,并探讨其机制 。
补充资料：受体激动剂
受体激动剂
receptor activating age?nts
能与受体结合，且可使受体激动，从而表现出相应的生理效应或药理作用的药物。例如乙酰胆碱，可与M胆碱受体结合，并使之激动，产生腺体分泌增加，心率减慢、血管扩张、支气管及胃肠道平滑肌收缩和瞳孔缩小等效应。
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