1) mutant prevention concentration
防细菌耐药突变体选择浓度
1.
AIM: To measure minimal inhibitory concentration(MIC),mutant prevention concentration(MPC) and mutant selection window(MSW) of fluoroquinolones for staphylococcus aureus strain ATCC29213,and isogenic mutants of strain ATCC29213 in vitro,MSW and the capacity of fluoroquinolones for restricting the selection of next-step staphylococcus aureus resistant mutants were evaluated.
目的:研究5种氟喹诺酮类药物(FQ)对金黄色葡萄球菌ATCC29213及其同源耐药突变体的最低抑菌浓度(MIC)、防细菌耐药突变体选择浓度(MPC)和突变选择窗(MSW),比较其防耐药变异能力,了解细菌对FQ耐药的发生发展过程。
2) mutant prevention concentration
防耐药突变浓度
1.
Mutant prevention concentration of fluoroquinolones against ciprofloxacin-susceptible Staphylococcus aureus;
喹诺酮药物对环丙沙星敏感金黄色葡萄球菌防耐药突变浓度
2.
Objective To measure mutant prevention concentration (MPC) of fluoroquinolones for Baumannii acinetobacter and its ciprofloxacin induced mutant strains.
目的研究环丙沙星、左氧氟沙星及加替沙星(均为氟喹诺酮类抗生素)对临床分离的鲍曼不动杆菌敏感株及其环丙沙星诱导的突变株的防耐药突变浓度(MPC),比较防耐药突变能力。
3.
Objective To measure the mutant prevention concentration(MPC) of fluoroquinolones to acinetobacter baumannii and its ciprofloxacin induced mutant strains.
目的研究3种氟喹诺酮类药物对临床分离的鲍曼不动杆菌敏感株及其环丙沙星诱导突变株的防耐药突变浓度(MPC),比较其防耐药突变能力。
3) mutant selection window
耐药突变选择窗
1.
Correlation of mutant selection window with selection of drug resistant mutants in rabbits;
耐药突变选择窗与细菌耐药的动物体内研究
2.
Preliminary study for narrowing mutant selection window of staphylococcus aureus by combination of levofloxacin and Vancomycin in vitro;
左氧氟沙星联合万古霉素缩小金黄色葡萄球菌耐药突变选择窗的初步研究
3.
Mutant selection windows of fluoroquinolones for isogenic resistant mutants of Staphylococcus aureus;
氟喹诺酮药物对金黄色葡萄球菌同源耐药突变株的耐药突变选择窗研究
4) Mutant prevention concentration
防耐药变异浓度
1.
Mutant prevention concentration of fluoroquinolones for Stenotrophomonas maltophilia;
4种氟喹诺酮类药物对嗜麦芽寡养单胞菌防耐药变异浓度的测定
2.
Mutant prevention concentration of fluorquinolones against klebsiella pneumoniae;
4种氟喹诺酮类药物对肺炎克雷伯杆菌的防耐药变异浓度
3.
Also to combine minimal inhibitory concentration(MIC),mutant prevention concentration(MPC)and mutant selection window(MSW)with pharmacokinetic parameters and then provide evidence for new strategies for restricting the development of resistance.
将它们对金黄色葡萄球菌的最低抑菌浓度(MIC)、防耐药变异浓度(MPC)、突变选择窗(MSW)与药代动力学参数结合,为制定新的抗菌药物用药策略提供依据。
5) mutant prevention concentration
防突变浓度
1.
Discussion and considerations on the mutant prevention concentration and mutant selective window;
对抗菌药物防突变浓度及突变选择窗两概念的探讨与思索
补充资料：细菌回复突变试验
分子式：
CAS号：
性质：又称爱姆斯试验。是一种最常用的检测化学物质致突变性/致癌性的短期试验方法。为Ames等在20世纪60年代建立的，利用组氨酸营养缺陷型鼠伤寒沙门氏菌的回复突变特性，以检测化学物质的致突变性/致癌性；用不同株的鼠伤寒沙门氏菌可以检测碱基对置换或移码突变。在测试系统中加入微粒体酶活化系统(S9组分)，以检测需经生物活化才具有致突变性的化学物质。爱姆斯试验与致癌性有较好地相关。
CAS号：
性质：又称爱姆斯试验。是一种最常用的检测化学物质致突变性/致癌性的短期试验方法。为Ames等在20世纪60年代建立的，利用组氨酸营养缺陷型鼠伤寒沙门氏菌的回复突变特性，以检测化学物质的致突变性/致癌性；用不同株的鼠伤寒沙门氏菌可以检测碱基对置换或移码突变。在测试系统中加入微粒体酶活化系统(S9组分)，以检测需经生物活化才具有致突变性的化学物质。爱姆斯试验与致癌性有较好地相关。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条