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1)  prodynorphin
前强啡肽
1.
) application antisense oligodeoxynucleotide (AS-ODN) to induce prodynorphin (Pro-Dyn) mRNA and observed the degree of inflammatory edema after the formalin injection in rats to prove whether the quantity of dynorphin A in nerve centre could effect the degree of periphery inflammation.
目的:利用鞘内注射前强啡肽mRNA的反义寡聚核苷酸,观察由福尔马林引起的大鼠后脚炎性水肿程度的变化,来证明脊髓背角中强啡肽(dynorphin,Dyn)A的量可能影响外周炎症反应的大小。
2.
Total RNA in hippocampus was extracted and primers of enkaphalin or prodynorphin were respectively added for RT-PCR reaction.
方法:采用单纯束缚的方法建立慢性束缚性应激的大鼠模型,提取海马总RNA,采用RT-PCR反应扩增脑啡肽和前强啡肽基因,比较二者在海马中的表达情况。
3.
Aim: To investigate the changes of enkaphalin mRNA and prodynorphin mRNA gene expression in rat brain regions with chro-(nic) immobilization stress and the influence of Chinese herbs.
目的:研究慢性束缚应激时大鼠海马脑啡肽和前强啡肽mRNA基因表达的变化以及逍遥散、四君子汤、金匮肾气丸三种中药复方对其的影响。
2)  preprodynorphin
前强啡肽原
1.
By using intrathecal administration of antisense oligodeoxynucleotide (AS-ODN) against preprodynorphin mRNA in rats, we observed that this treatment could block both the formalin-induced behavioral nociceptive responses and the increased expression of dynorphin A (1-8) in the dorsal horn, with the increased expression of c-Fos protein being unchanged.
应用大鼠鞘内预先注入对抗前强啡肽原表达的反义寡聚核苷酸技术 ,观察了此处理对动物后脚掌注射福尔马林 ( 5 %,1 0 0μl)诱发的行为痛反应的影响 ,同时在行为检查的 1 h后立即用免疫组化技术检测了大鼠腰髓背角 c-Fos蛋白和强啡肽 A( 1 -8)的表达。
3)  preprodynorphin gene
前强啡肽基因
4)  preprodynorphin mRNA
前强啡肽原mRNA
1.
Objective:To investigate the effects of long-term administration of morphine on preprodynorphin mRNA (PPD mRNA) levels in different brain sites of rats, including hypothalamus, hippocampus and striatum.
目的·· :观察慢性腹腔注射(ip)吗啡对大鼠下丘脑、海马、纹状体中前强啡肽原mRNA(PPDmRNA)表达的影响。
5)  proenkephalin
前脑啡肽
1.
Decreased expression of proenkephalin mRNA in defined regions of morphine dependent rats;
吗啡依赖大鼠部分脑区前脑啡肽基因表达改变
6)  dynorphin
强啡肽
1.
Effect of N-nitro-L-arginine on the Inhibition of Morphine Physical Dependence in Rats and Its Dynorphin A Mechanism;
N-硝基-L-精氨酸抑制大鼠吗啡身体依赖的强啡肽机制
2.
Changes of extracellular adenosine concentration in spinal cord in dynorphin-induced paralysis rats;
强啡肽A致截瘫大鼠脊髓组织细胞外腺苷浓度的变化
3.
Research on mechanism of non-opioid receptor in dynorphin-induced spinal cord injury;
强啡肽致脊髓损伤中非阿片样受体机制的研究
补充资料:强啡肽 A (1-13)
分子式:C75H126N24O15
分子量:1603.97
CAS号:72957-38-1

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