1) TNF-α
α肿瘤坏死因子
1.
Study on rat small airway epithelium injury induced by Klebsiella pneumoniae and relation with TNF-α in the lung;
肺炎克雷伯菌引起大鼠小气道上皮细胞损伤及与肺内α肿瘤坏死因子关系的探讨
2.
Objective:To study the mRNA expressions of TNF-α,IL-6 and IL-1β in BALB/c mouse skin treated by 5% imiquimod cream.
方法:以5%咪喹莫特乳膏刺激BALB/c小鼠皮肤,用逆转录(RT)-PCR法检测皮肤组织中α肿瘤坏死因子(TNF)-α、白介素(IL)-6及IL-1βmRNA的含量。
3.
The ALT, TNF-α levels in serum and the nitric oxide (NO) levels in liver tissue were determined in control and the treated groups.
方法ConA尾静脉注射制备小鼠免疫性肝损伤模型,在ConA注射前1h腹腔注射Glucan,观察正常对照组、ConA损伤组、Glucan/ConA组肝损伤的情况,检测血清谷丙转氨酶(ALT)、α肿瘤坏死因子(TNF-α)及组织中一氧化氮(NO)含量的变化,并用DNAladder检测肝细胞凋亡的变化。
2) Tumor necrosis factor-alpha
α肿瘤坏死因子
1.
Tumor necrosis factor-alpha(TNF-α) is a cytokine mediating inflammatory reaction and immune responses, and has various biological activities.
α肿瘤坏死因子是介导炎症反应和免疫反应的细胞因子,具有广泛的生物学活性。
2.
MethodsThe effects of interleukin-1 beta (IL-1 β) and/or tumor necrosis factor-alpha (TNF-α) on cultured human RPE were examined by MTT and 3H-TdR incorporation assay.
目的观察白介素１ β （ＩＬ－１ β）和α肿瘤坏死因子(ＴＮＦ－α）对培养的人视网膜色素上皮细胞(ＲＰＥ）生长的影响，了解在增生性玻璃体视网膜病变（ＰＶＲ）中炎前因子的调控机制。
3) tumor necrosis factor-α
肿瘤坏死因子-α
1.
Expressions of vascular endothelial growth factor,tumor necrosis factor-α,CD1a and γδTCR~+ T in pleural effusion and peripheral blood and their diagnostic value analysis for tuberculosis and lung cancer;
血管内皮生长因子、肿瘤坏死因子-α、CD1a、γδTCR~+ T在胸腔积液和外周血中表达及其对肺结核和肺癌的诊断价值
2.
Effect of berberine hydrochloride on the expression of interleukin-1β and tumor necrosis factor-α in periodontal tissues in rats;
盐酸小檗碱对大鼠牙周组织中白细胞介素-1β和肿瘤坏死因子-α表达的影响
3.
Effect of Gymnadenia conopsea alcohol extract on pulmonary fibrosis of rats exposed to silica and the expression of tumor necrosis factor-α;
手掌参醇提取物处理染矽尘大鼠肺纤维化及肿瘤坏死因子-α表达的变化
4) Tumor necrosis factor α
肿瘤坏死因子α
1.
Dynamical detection of tumor necrosis factor α mRNA expression in rat spinal cord of neuropathic pain using FQ-RT-PCR;
荧光定量PCR动态检测神经病理性疼痛大鼠脊髓肿瘤坏死因子α表达变化
2.
Alteration of serum tumor necrosis factor α concentration in different kinds of diabetic mice;
不同类型的糖尿病模型小鼠血清肿瘤坏死因子α水平的变化
3.
Effects of Centalla asiatica combining emodin on complement C3 in glomerular mesangial cells stimulated by Tumor Necrosis Factor α;
积雪草苷合大黄素对肿瘤坏死因子α诱导的肾系膜细胞C3表达的影响
5) tumor necrosis factor-α(TNF-α)
肿瘤坏死因子-α
1.
Objective: To investigate the effect of Ghrelin on plasminogen activator inhibitor-1(PAI-1) mRNA expression in HepG2 cells induced by tumor necrosis factor-α(TNF-α) and the effect of nuclear factorκB(NF-κB).
目的:探讨Ghrelin对肿瘤坏死因子-α(TNF-α)诱导的HepG2细胞纤溶酶原激活物抑制剂-1(PAI-1)mRNA表达的影响及核因子-κB(NF-κB)在其中的作用。
2.
Objective To investigate significance of serum tumor necrosis factor-α(TNF-α) detection for diagnosis of intrahepatic cholestasis of pregnancy(ICP).
目的探讨肿瘤坏死因子-α在妊娠肝内胆汁淤积症发病中的作用。
3.
Objective:To study the pathology of liver injury in rats with obstructive jaundice and the relationship between Hepatic injury and Intercellular Adhesion Molecule-1(ICAM-1),Tumor Necrosis factor-α(TNF-α),Interleukin-1(IL-1).
目的:初步探讨大鼠梗阻性黄疸模型(obstructive jaundice,OJ)时肝脏损伤的病理变化及细胞间黏附分子-1(ICAM-1)、肿瘤坏死因子-α(TNF-α)、白介素-1(IL-1)与肝损伤的关系。
6) tumor necrosis factor-α
肿瘤坏死因子α
1.
Expressions of Tumor Necrosis Factor-α,Interleukin-6 and Interleukin-10 and Pathologic Changes of Myocardium After Myocardial Infarction in Mice;
小鼠心肌梗死后肿瘤坏死因子α、白细胞介素6和白细胞介素10表达变化及心肌病理改变
2.
Serum hyaluronic acid,tumor necrosis factor-α,vascular endothelial growth factor,NO,and Se levels in adult patients with Kashin-Beck disease;
成人大骨节病血清透明质酸、肿瘤坏死因子α、血管内皮生长因子、NO和硒含量检测
3.
Changes of serum bone glaprotein propeptide and tumor necrosis factor-α levels in patients with rheumatoid arthritis before and after treatment;
类风湿性关节炎患者治疗前后血清骨钙素及肿瘤坏死因子α水平的变化
补充资料：肿瘤坏死因子
分子式：
CAS号：
性质：又称恶液质素(cachectin)，淋巴毒素(lymphotoxin；LT)。注射卡介苗短小棒状杆菌和酵母多糖等制剂，再以内毒素攻击在小鼠、大鼠和兔等多种动物的血清中出现的一种能引起肿瘤出血性坏死的活性成分。含有唾液酸和半乳糖胺的一种糖蛋白，分子量约150 000。根据其产生来源和结构不同，可分为TNF-α和TNF-β两类，前者有单核-巨噬细胞产生，后者有活化T细胞产生，现已有基因重组技术制备。两类TNF的基本生物活性相似，除具有杀伤肿瘤细胞外，还有免疫调节，参与发热和炎症的发生。大剂量TNF-α可引起恶液质，医疗上可单独或白细胞介素2联合用于治疗肿瘤。
CAS号：
性质：又称恶液质素(cachectin)，淋巴毒素(lymphotoxin；LT)。注射卡介苗短小棒状杆菌和酵母多糖等制剂，再以内毒素攻击在小鼠、大鼠和兔等多种动物的血清中出现的一种能引起肿瘤出血性坏死的活性成分。含有唾液酸和半乳糖胺的一种糖蛋白，分子量约150 000。根据其产生来源和结构不同，可分为TNF-α和TNF-β两类，前者有单核-巨噬细胞产生，后者有活化T细胞产生，现已有基因重组技术制备。两类TNF的基本生物活性相似，除具有杀伤肿瘤细胞外，还有免疫调节，参与发热和炎症的发生。大剂量TNF-α可引起恶液质，医疗上可单独或白细胞介素2联合用于治疗肿瘤。
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参考词条