1) 6β-hydroxycortisol
6β-羟基氢化可的松
1.
Objective: To investigate the activity of CYP3A enzyme, an effective method of HPLC (Gradient elution)for determining the concentration of 6p-hydroxycortisol and cortisol in urine and measuring the ratio of 6β-hydroxycortisol and cortisol was established.
目的:用HPLC法(梯度洗脱)测定尿液中6β-羟基氢化可的松(6β-OHC)和氢化可的松(HC)的含量,计算6β-OHC和HC的比值以反映人体中CYP3A酶的活性,为其研究提供有效的分析手段。
2.
METHODS After collecting urine for 24 hours,the urinary concentrations of HC and 6β-hydroxycortisol(6β-OHC) were determined by high performance liquid chromatography(HPLC).
方法:收集24h尿液,以HPLC法测定尿液中氢化可的松(HC)与6β-羟基氢化可的松(6β-OHC)的含量,以6β-OHC/HC来评估细胞色素P4503A酶的活性。
3.
The endogenous 6β-hydroxycortisol and cortisol concentrations in the urine were determined.
方法直接收集20例精神病住院患者晨尿液,测定尿液中内源性氢化可的松与6β-羟基氢化可的松的含量,以6β-羟基氢化可的松/氢化可的松来评估CYP3A酶的活性。
2) 6β-OHE
6β-羟基可的松
3) Hydrocortisone
[英][,haidrə'kɔ:tisəun] [美][,haɪdrə'kɔrtəson]
氢化可的松
1.
Control Hydrocortisone Fermentation Process by Polarimetry;
旋光法用于氢化可的松生产过程的控制
2.
Bioconversion of compound S into hydrocortisone using a novel process of twi-run sequence bioconversion by the mycelium of Curvularia lunata AS 3.4381;
静息细胞连续两批次生物催化生产氢化可的松
3.
The Improvement of Stereoselectivity of Hydrocortisone Transformation;
提高氢化可的松发酵过程中的微生物转化效率的初探
4) Cortisol
[英]['kɔ:tisɔl] [美]['kɔrtɪsɑl]
氢化可的松
1.
Simultaneous Determination the Contents of Cortisol and Cortisone in Serum by HPLC;
RP-HPLC法同时测定人血清中内源性氢化可的松与可的松的含量
2.
Simultaneous Determination of Endogenous Cortisol and Its Metabolite in Urine by HPLC-DAD;
高效液相色谱-二极管阵列法同时检测尿中内源性氢化可的松及其代谢产物
3.
Determination of CYP3A activity in vivo by the ratio of urinary endogenous 6β-hydroxycortisol to cortisol;
内源性氢化可的松为探针的体内CYP3A活性测定
5) 6β-hydroxylation
6β-羟基化代谢率
1.
RESULTS:In the study on correlation between F and E 6β-hydroxylation metabolism and the C/D ratio of CsA in renal transplant recipients,there were inverse correlations between 6β-OHF+6β-OHE/F+E and the C/D ratio of CsA,6β-OHF +6β-OHE/F+E and weight-normalized C/D ratio of CsA in all, male and female subjects.
目的:研究肾移植患者尿中氢化可的松(F)及可的松(E)6β-羟基化代谢率与环孢霉素(CsA)血药浓度剂量比的相关性。
6) 6-methlhydrocortisone
6-甲基氢化可的松
1.
Study on biotransformation of 6-methlhydrocortisone in aqueous two-phase systems;
双水相体系中甾类化合物6-甲基氢化可的松的生物转化研究
补充资料：11-表氢化可的松
分子式：C21H30O5
分子量：362.47
CAS号：566-35-8
性质：结晶化合物。熔点217-220℃（部分分解）。溶于乙醇、甲醇、丙酮，略溶于氯仿，微溶于水、乙醚。
制备方法：暂无
用途：可的松醋酸酯、确炎舒松A醋酸酯、肤轻松醋酸酯的中间体。
分子量：362.47
CAS号：566-35-8
性质：结晶化合物。熔点217-220℃（部分分解）。溶于乙醇、甲醇、丙酮，略溶于氯仿，微溶于水、乙醚。
制备方法：暂无
用途：可的松醋酸酯、确炎舒松A醋酸酯、肤轻松醋酸酯的中间体。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条