Clinical anmd pathologicl analysis of isolated hematurian in 37 children;

Methods Paraffin-embedded renal biopsy tissue sections from 28 children with primary nephrotic syndrome(PNS), 18 children with acute glomerulonephritis(AGN), 20 children with Henoch-Schoenlein purpura nephritis(HSPN) and 22 children with isolated hematuria(IHU) were examined by immunohistochemical staining with anti-FGFR 4 monoclonal antibody.

Results The main clinical manifestations of IgM nephropathy in children included nephritic syndrome (NS, 17 cases), isolated hematuria (13 cases), and others such as proteinuria, proteinuria combined with hematuria.

Objective:Simple hematuria is a common kidney syndrom.

To observe the clinical efficacy of simple hematuria treated on syndrome differentiation, 93 subjects were randomized into two groups: treatment group in which 47 cases were treated on syndrome differentiation and control group in which 46 cases were treated by western medicine, with a course of 6 months.

Objective To investigate renal immunopathologic changes and the expression of transforming growth factor-β(TGF-β)in tubular in children with single hematuria,and to explore the role of TGF-β in the pathogenesy of it.

ObjectiveTo observe the renal immunopathologic changes and expression of vascular endothelial growth factor(VEGF) of renal tubule in children with single hematuria,and to explore the role of VEGF in the pathogenesy.