Expression, purification and immunogenicity of a novel hepatitis E virus-like particle;

Expression,purification and immunogenicity of human papillomavirus type 11 virus-like particles from Escherichia coli

Influence of insertion of porcine circovirus type 2 ORF2 gene into the 3′ end of porcine parvovirus VP2 gene on formation of virus-like particle

Construction and expression of virus-like particles containing SARS CoV RNA;

Immune efficacy of Newcastle disease virus-like particles;

Expression, purification and immunogenicity analysis of HPV type 18 virus-like particles from Escherichia coli

Objective To express full length VP60 gene of rabbit hemorrhagic disease virus (RHDV) in insect-baculovirus system,and to characterize the formation of RHDV-Like particles (RHDV-VLPs) and its biological properties,and verify the potential of RHDV-VLPs as detection antigen and subunit vaccine to RHD.

As a efficient investigation method, Virus-Like Particles (VLPs) technique has play an important role in the study of character, polymorphism, vaccine of many viruses.

Virus-like particles (VLPs) is a non-nucleic acid virus particles,with the same morphology to the natural virus particles.

Virus-like particles(VLPs)are highly organized viral capsid proteins that self-assemble from virus-derived structural antigens, which resemble the overall structure of virus particles and thus preserve the native antigenic conformation of the immunogenic proteins.

Expression and purification of HPV 18 L1 virus like particles and preparation of guinea pig antiserum against HPV 18 L1 VLP

The virus like particles (VLPs) in insect cells.

To obtain the virus like particles (VLPs) of human papillomavirus type 4 (HPV4), the cloned vector pUHPV4 L 1 containing the L 1 gene was digested by EcoRⅠ and BamHⅠ .