Objective To study the change in serum high mobility group - 1 (HMG - 1) protein in patients with multiple trauma and determine its relationship to severity of trauma and multiple organ dysfunction syndrome (MODS).

Organ dysfunction (OD) and multiple organ dysfunction syndrome (MODS) are one of the major complications and important death cause of trauma, and the mortality is very high in clinic because of lacking special and effective therapeutic strategies.

Multiple organ dysfunction syndrome(MODS) is a common clinical challenge if the systemic inflammatory response syndrome could not be properly cured.

Objective: To study Collapse Syndrome and the diagnosis of MODS.

Myocardiac change in multiple organ dysfunction syndrome rat at high altitude;

Impact of gender and age on multiple organ dysfunction syndrome and inflammatory cytokines after multiple injuries

[Objective]To study treatment on myocardium in multiple organ dysfunction syndrome rat at high altitude through Granulocyte Colony Stimulating Factor(G-CSF).

Objective: To explore myocardial necrosis could occur in critical care patients with acute non-cardiac illness while followed MODS and to search for indexes of cardiac necrosis.

In theprocess of SIRS pathophysiology, much ingredient of damage can induceexcessive stress response of body and activate immune cells, which enlargethe inflammatory reaction in cascade mod and can formatted vicious cycle,finally will lead to SIRS and multiple organ dysfunction syndrome(MODS).