Researches have suggested that the increased AngⅡ can promote productions of numerous inflammatory factors that mediated the target organ damage caused by AngⅡ.

Aim:To investigate the relationship between early stage target organ damage and erythrocyte L arginine transport in spontaneously hypertensive rats (SHR).

ObjectiveTo investigate the relationship between mRNA expression of inducible nitric oxide synthase (iNOS) and organ injury, and the effect of Salviae Miltiorrhizae on iNOS mRNA in severe acute pancreas (SAP) rats.

Our previous stUdies have found that BPV is a contributing factor of endorgan damage (EOD), Which includes myocardial hypertrophy, vascularremodeling, kidney damage and so on.

The relationship between blunted reduction of nighttime pulse pressure and target organ damage in elderly hypertensive patients;

Ambulatory blood pressure parameters and target organ damage in 140 primary hypertension patients;

Association between morning blood pressure surge and target organ damage in elderly patients with essential hypertension

Objective To explore the relationship between pulse pressure and target organs damage in aged patients with essential hypertension (EH).

Objectives This investigation was designed to study relationship between Serum pro-collagen Ⅰ(PC Ⅰ) , pro-collagen Ⅲ(PC Ⅲ) , tissue inhibitor of matrix metalloproteinase-1(TIMP-1)and target organs damage (TOD) in essential hypertension by measuring serum Concentration of PC Ⅰ , PC Ⅲ , TIMP-1 in normal subjects and patiens with essential hypertension.

Conclusion The higher incidence rate of heart,brain and blood vessel events are related with artery elasticity decreasing;Target organs damage is close correlation with baPWV increaseing in patients with essential hypertension.