Objective:Abstract Objective: To explore the relationship of myocardial matrix metalloproteinase-3(MMP-3) and tissue inhibitor of metalloproteinase-1(TIMP-1) with angiotensinⅡ(AngⅡ) and its roles in myocardial collagen remodeling in mice with Coxsackievirus myocarditis(VM).

The quantity of myocardial collagen was measured by chloramines T.

Objective:In order to provide a new way for treating hypertension and the early heart protection, we studied the change of myocardial collagen network during every stage of the spontaneously hypertension.

Objective:To explore the role of myocardial matrix metalloproteinases-3 (MMP-3), tissue inhibitor of metalloproteinases-1 (TIMP-1) in mice with viral myocarditis(VM) and their relationships with myocardial collagen.

Activation of extracellular signal regulated kinase in myocardial remodeling in patients with congestive heart failure;

A study on protective mechanism of calcium channel blockade in the rat myocardial remodeling;

Vitamin E reduces the oxidative stress and myocardial remodeling induced by aldosterone

Effects of fosinopril and metoprolol on cardiac remodeling and plasma levels of neurohormones in heart failure patients;

Role of cytokines in myocardiac remodeling;

Since mid-1990s, it has been recognized that cardiac remodeling constitutes the pathophysiological basis leading to the development of CHF.

Effect ofβ_3adrenoceptor agonist BRL37344 on the plasma level of TNFα、AngⅡ、 ET-1 and the myocardium remodeling in rat;

Myocardium remodeling autoantibodies against β_1-receptors and clinical meaning of immune function;

Objective To explore the effect of BRL-37344 (BRL),a kind of β_3-adrenoceptor(β_3-AR) agonist, on the plasma level of tumor necrosis factor-α(TNF-α)?angiotensionⅡ(AngⅡ)?Endothelin-1(ET-1)and myocardium remodeling of the rat with progressive congestive heart failure(CHF).