1) sEPSC
自发性兴奋性突触后电流
1.
After cells were opened 10~15 min,90 μl intralipid or 100 μmol/L propofol was administered for 40 minutes and sEPSC were recorded by whole-cell patch-clamp technique.
目的:研究异丙酚对大鼠海马CA1区自发性兴奋性突触后电流(sEPSC)的影响。
2.
In 64 examined SG neurons, at a holding potential of –70 mV, perfusion of melittin (1 ?M) enhanced the spontaneous excitatory postsynaptic current (sEPSC) frequency by 65±6% (n=51) and the sEPSC amplitude by 43±5% (n=20).
结果发现: 当固定电位为-70 mV时,在所记录的64 个SG 细胞中,灌流melittin (1 ?M), 51个SG 细胞的自发性兴奋性突触后电流 (spontaneous excitatory postsynaptic currents,sEPSCs) 的频率增加65±6%,20 个SG 细胞的sEPSCs 的振幅增加了43±5%; Melittin的这两种作用不能被TTX抑制, 但能被磷酯酶A2(PLA26)的抑制剂 4-BPB (4-bromophenacyl bromide, 10 ?M) 完全抑制; 体内PLA2 反应的产物花生四烯酸 (arachidonic acid, 50 ?M) 能使SG 细胞sEPSC 的频率增加 88±18% (n=6),但对其振幅无明显影响 (为对照的102±1%, n=4);SG 细胞sEPSC 的频率的增加依赖于melittin的剂量。
2) mEPSCs
自发兴奋性突触后电流
1.
The mEPSCs (miniature excitatory postsynaptic currents) was measured with patch clamp.
方法 采用PI染色和双重免疫荧光技术定量观察神经元死亡和突触GluR2含量变化 ,以膜片钳技术检测自发兴奋性突触后电流(mEPSCs)的变化。
3) excitatory postsynaptic currents(EPSCs)
兴奋性突触后电流(EPSCs)
4) EPSC
兴奋性突触后电流
1.
Objective To investigate the effects of propofol on the whole-cell excitatory postsynaptic current(EPSC)in hippocampal CA1 pyramidal neurons and analyze the role of GABA_ A receptor and glycine receptor in propofol anesthesia.
目的研究丙泊酚对大鼠海马CA1区电刺激诱发兴奋性突触后电流(EPSC)的影响,分析γ-氨基丁酸(GABA)受体和甘氨酸受体在丙泊酚麻醉中的作用。
2.
EPSCs were recorded by whole-cell patch-clamp technique.
方法:分离大鼠海马半脑,切出400μm厚度的海马脑片,全细胞膜片钳记录戊四氮+咪唑安定组,戊四氮+脂肪乳剂组,戊四氮+丙泊酚组海马CA1区神经元兴奋性突触后电流(EP-SC)变化。
5) excitatory postsynaptic current (EPSC)
兴奋性突触后电流(EPSC)
6) excitatory postsynaptic currents
兴奋性突触后电流
1.
Method Blind whole-cell voltage-clamp recordings were performed on the CA1 pyramidal cells in adult rat hippocampal slices to examine and analyze the effect of bath-applied kainate (10 μmol/L) on CA1 afferent fiber-evoked excitatory postsynaptic currents (EPSCs) and inhibitory postsynaptic currents (IPSCs), respectively.
方法对成年大鼠海马脑片CA1区锥体细胞采用“盲法”全细胞电压钳记录,分别检测和分析KA (10 μmol/L)对CA1传入纤维引出的兴奋性突触后电流和抑制性突触后电流的影响。
2.
Objective To investigate mechanisms ending the critical period of visual plasticity,the amino-3-hydroxy-5-methylisoxazole-4-propionicacid(AMPA) receptor-mediated excitatory postsynaptic currents(AMPA-EPSCs) in rat visual cortex was studied around the end of cirtical period of plasticity.
目的为了探索视觉发育可塑性关键期终止机制,对可塑性关键期终止前后,正常大鼠视皮层α-氨基-3-羟基-5-甲基-4-异恶唑丙酸(amino-3-hydroxy-5-methylisoxazole-4-propionicacid,AMPA)受体介导的兴奋性突触后电流进行了研究。
补充资料：紧张性兴奋
紧张性兴奋
精神分裂症紧张型患者的一种表现。在精神运动性兴奋时常表现为刻板重复的言语或动作，也可出现突然的短暂的冲动行为。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条