Objective:　The aim of this study was to compare the discrepancy between the stiffnesses of the normal and hypertrophic isolated myocardium in rabbits by analysing the stress-strain relationships of free wall with our prototype load-deformation experimental device, and to explore the feasibility of detecting myocardiul stiffness by indentation test.

Aim and Methods: To test the direct effects of naloxone (an non selective opioid antagonist) on heart, we employed the isolated atrial preparations to investigate the inotropic and chronotropic actions of naloxone.

Method The effect of resveratrol on sinus frequency of isolated right atrium was observed,and the changes were detecued in the presence of different potassium channels blocking agents and the underlying mechanisms were studied.