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1)  uninephrectomized diabetic rats
单肾切除糖尿病大鼠
1.
Objective: To explore the effects of angiotensin Ⅱ type 1 receptor antagonist(AT1RA) losartan and hydroxy-methyl-glutaryl coenzymeA reductase inhibitor(HMG-CoA RI) simvastatin on transcription of BAX and BCL-2 genes of uninephrectomized diabetic rats.
目的:探讨氯沙坦和辛伐他汀对单肾切除糖尿病大鼠肾脏凋亡相关基因BAX/BCL-2mRNA的影响。
2)  diabetic nephropathy rats
糖尿病肾病大鼠
1.
Objective:To observe the effect of Chinese Herb recipe on the expression of ERK1/2`lipidic`metabolism`oxygen-derived free radicals` in early diabetic nephropathy rats,try to explore the possible mechanism of ERK1/2 activity and the protection role of Chinese Herb recipe on diabetic nephropathy.
目的:观察中药复方对糖尿病肾病大鼠肾皮质中磷酸化胞外调节蛋白激酶活性变化、脂质代谢、氧化-抗氧化系统及肾脏病理变化的影响。
3)  STZ DN Rats Model
STZ糖尿病肾病大鼠模型
4)  Diabetic nephropathy animal model
糖尿病肾病大鼠模型
5)  experimental diabetic nephropathy rat
实验性糖尿病肾病大鼠
6)  diabetic rat
糖尿病大鼠
1.
Effect of valsartan on expression of receptor for advanced glycation end-products in renal tissues of diabetic rats;
缬沙坦对糖尿病大鼠肾组织糖化终末产物受体表达的影响
2.
Expression and identification of novel genes differentially expressed in diabetic rats supplemented with zinc;
糖尿病大鼠补锌后新基因片段表达与鉴定
3.
Protective role of mycophenolate mofetil on renal tubulointerstitial injury of diabetic rats;
霉酚酸酯对糖尿病大鼠肾小管-间质损伤的保护作用
补充资料:肾切除术


肾切除术
nephrectomy

将病肾切除的手术。适应于①损伤、结石、结核、巨大肾积水或积脓以及其他病变,累及一侧肾,严重损坏肾实质,使之失去功能或完全无功能,而对侧肾功能良好者;②一侧良性或恶性肿瘤;③一侧肾动脉狭窄、肾发育不全等,导致肾缺血,产生肾血管性高血压,不能施行血管重建手术,而对侧肾功能良好者。有两种切口:一是腰部斜切口,二是12肋切口。输尿管的处理一般是切除输尿管上段。肾癌的肾切除要切除全部输尿管,肾结核的输尿管尽量在低位切断。一般先处理输尿管。再处理肾蒂,而肾癌肾切除时最好先处理肾蒂的血管再处理输尿管,并将肾、肾周脂肪囊、肾蒂淋巴结和全部输尿管作整块切除。术中要注意勿损伤肾上腺和肾血管。术后48~72小时拔除切口引流物,术后7~10日拆除皮肤缝线。
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