Tertrramethylpyrazine (TMPz) Inhibit the Glutamate-Induced-Apoptosis of PC-12 by Down-Regulating the Ratio of Bax/Bcl2 and Caspase9;

Changes in caspase-3,9 activity and mRNA expression of normal human hepatocyte HL-7702 cell in the process of apoptosis induced by glycodeoxycholate.;

Dynamical analysis of caspase-3,8,9 and mRNA activities in simvastatin-induced apoptotic K562 cells;

Regulatory Effect of Caspase in Apoptosis of Skin Tumors;

Effects of Caspase on Neuron Apoptosis of Cerebral Ischemia/reperfusion Injury;

Evidence for Oldenlandia diffusa-evoked cancer cell apoptosis through superoxide burst and caspase activation;

Triptolide induces apoptosis in myelodysplastic syndromes MUTZ-1 cells through activation of caspases and down-regulation of IAPs;

Effect of Supplement Energy and Nourish Lung Herbs on Drug-Resistance Lung Cancer with Mechanisms of Mitochondrial and Caspase Signal;

Purpose: To study whether sesquiterpene lactones(SLs) have the inducible apoptosis effect on human nasopharyngeal carcinoma (NPC) and it s relation with the mechanism of caspase activation, Methods: NPC cell line (CNE1) was treated with parthenolide(PN),the principal active component of SLs.

[Methods] The invasiveability,the survivin-ΔEx3 mRNA and Caspase-3 mRNA were measured by RT-PCR,the G_1 cells and ap- optosis cells were measured by FCM.

Alternations of the apoptosis rate of PMN and the expression of caspase-3, caspase-8 in PMN were studied with flow cytometer and Western blotting technique.

Results Caspase-9-and caspase-3-positive cells were detected in epidermis,hair follicles,and sebaceous glands in control skin.