1) mitochondrial permeability transition
线粒体通透性转换
1.
Objective To study the effect of mitochondrial permeability transition(MPT) after ischemia/reperfusion(I/R), and to find the relationship between MPT and apoptosis of hepatocytes in rats.
目的观察大鼠肝脏常温缺血再灌注后肝细胞线粒体通透性转换(mitochondrialpermeabilitytransition,MPT)作用及其与肝细胞凋亡的关系;同时观察线粒体膜通透性转换孔(mitochondrialpermeabilitytransitionpore,PTP)开放抑制剂环孢素A(CsA)对MPT的抑制作用,以及对肝细胞凋亡的影响和可能的机制。
2.
Objective: To investigate the effect of ischemic preconditioning on neural function, mitochondrial permeability transition and level of cyto- chrome C in the hippocampal tissue, in order to study further the brain protection mechanism produced by ischemic preconditioning.
目的:研究脑缺血预处理对再次脑缺血的神经功能、细胞形态、线粒体通透性转换(mitochondrial permeability transition,MPT)及细胞色素C(cytochrome c,CytC)水平的影响,进一步探讨脑缺血预处理的脑保护机制。
2) mitochondria permeability transition
线粒体通透性转换
1.
Involvement of peripheral benzodiazepine receptor in the regulation of rat cardiac mitochondria permeability transition;
外周苯二氮受体参与调控大鼠心肌线粒体通透性转换
3) mitochondrial permeability transition pore
线粒体通透性转换孔
1.
The role and mechanism of mitochondrial permeability transition pore in ischemic postconditioning;
线粒体通透性转换孔在缺血后处理中的作用和机制
2.
The opening state of mitochondrial permeability transition pore determines the mitochondrial membrane permeability, which is crucial to regulate apoptosis: cytochrome c is released from mitochondria to cytoplasm, activates caspases via combining Apaf-1 and ATP, initiating caspases cascade, .
线粒体膜通透性转换孔的开放状态决定了线粒体膜的通透性,在调节细胞凋亡中起了非常关键的作用:细胞色素c从线粒体释放到胞浆中,与凋亡蛋白激活因子-1和ATP结合可活化caspases,启动caspases的级联反应,引起底物蛋白水解、凋亡小体形成等,诱发细胞凋亡;Bcl-2和Bax是细胞凋亡过程中两个重要的调控基因,Bcl-2的表达增强会抑制细胞凋亡,而Bax的过度表达则会促进细胞凋亡;诱导细胞凋亡时发生的线粒体Ca~(2+)摄取既诱发线粒体通透性转换孔的开放也介导线粒体发生钙诱导的钙释放,胞浆高浓度的钙能激活各种蛋白激酶而诱导细胞凋亡的发生。
3.
Aim: To investigate the role of mitochondrial permeability transition pore(MPTP) in the cardioprotection by remote preconditioning(RPC).
目的:观察线粒体通透性转换孔在远距预处理心肌保护中的作用。
4) mitochondrial permeability transition pore
线粒体膜通透性转换孔
1.
The effect of copper on the mitochondrial permeability transition pore was significant,resulting in swelling of mitochondria to some degree which was manifested by decr.
结果显示,铜对线粒体膜通透性转换孔有较显著的影响,造成线粒体不同程度的肿胀,表现为线粒体悬液在540 nm处的吸光值下降,且铜浓度越高,吸光值下降越明显,在孵育6 min后3种浓度的吸光值下降百分比差异显著(P<0。
5) Mitochondrial permeability transition pore
线粒体通透转换孔
1.
Mitochondrial permeability transition pore and myocardial ischemia-reperfusion injury;
线粒体通透转换孔与心肌缺血-再灌注损伤
2.
ATP-sensitive potassium channel and mitochondrial permeability transition pore involve in cardioprotection of polydatin
ATP敏感性钾通道和线粒体通透转换孔参与白藜芦醇苷的心肌保护作用(英文)
3.
Objectives:The purpose of this study is with randomized controlled methods,by observing the differents among the four groups of SD rats of clean grade: cytochrome C oxidase activity and mitochondrial permeability transition pore\' s activity to explore the relations between the mitochondrial oxidative damage and osteoporosis.
结果:线粒体通透转换孔30min/0minOD比值比较显示,空白对照组和尼尔雌醇组与模型组有明显差异(P<0。
6) mitochondrial permeability transition pore
线粒体膜通透转换孔
补充资料：毛细血管通透性
毛细血管通透性
capillary permeability
毛细血管壁允许物质透过的能力。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条