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1)  deacetylase
去乙酰化酶
1.
The activity of deacetylases was measured with an ELISA-like reaction.
方法应用细胞免疫荧光实验观察组蛋白乙酰化水平变化,并基于ELISA样反应方法检测组蛋白总体去乙酰化酶的活性变化,荧光定量PCR检测乙酰化酶mRNA表达,荧光定量PCR和Western印迹检测去乙酰化酶表达变化及曲古霉素A对相应酶表达的影响。
2)  SIRT1 deacetylase
SIRT1去乙酰化酶
3)  histone acetyltransferase (HAT)/histone deacetylase (HDACs)
组蛋白乙酰化酶/组蛋白去乙酰化酶
4)  deacetylation [diə,siti'leiʃən]
去乙酰化
1.
Aim To investigate whether the mechanism of curcumin antagonizing tumor correlates with histone acetylation/deacetylation,which is regarded as modulation of transcription level.
目的研究姜黄素对淋巴瘤细胞系Raji细胞的抑制增殖作用,并在组蛋白乙酰化/去乙酰化水平对其抗肿瘤机制进行探讨。
5)  histone deacetylases
组蛋白去乙酰化酶
1.
Synthesis and activity study of a new series of histone deacetylases(HDACs) inhibitors of N-hydroxycinnamamide derivatives;
一组新的N-羟基肉桂酰胺类组蛋白去乙酰化酶抑制剂的合成和初步活性研究
2.
Histone acetyltransferases(HAT) and histone deacetylases(HDACs) as the corresponding enzymes regulate the change of histones in two antagonist forms,acetylated or deacetylated.
组蛋白乙酰转移酶(HAT)和组蛋白去乙酰化酶(HDAC)调节组蛋白乙酰化程度,HDAC在基因表达和染色体形成等方面起着重要的调节作用。
3.
Histone acetyltransferases (HATs) and histone deacetylases (HDACs) are emerging as important components of protein complexes that affect the dynamics of chromatin folding during gene transcription.
组蛋白乙酰转移酶(histone acetyltransferases, HATs)和组蛋白去乙酰化酶(histone deacetylase, HDACs)可以通过调节组蛋白或转录因子的乙酰化状态来调节基因的活化或沉默。
6)  Histone deacetylase
组蛋白去乙酰化酶
1.
Differentiation of PLZF-RARα-positive U937 leukemic cells induced by histone deacetylase inhibitor trichostatin A in combination with all-trans retinoic acid;
组蛋白去乙酰化酶抑制剂曲古菌素A联合全反式维甲酸诱导PLZF-RARα阳性U937细胞分化
2.
Synergistic cytotoxicity effect of histone deacetylase inhibitor combined with paclitaxel on lung cancer cell lines and its mechanism
组蛋白去乙酰化酶抑制剂协同紫杉醇对人肺癌细胞株抑制作用及机制
3.
Relationship Between Systemic Inflammation and Activity of Histone Deacetylase in Peripheral Blood Mononuclear Cells from COPD Patients
慢性阻塞性肺病外周血单个核细胞中的组蛋白去乙酰化酶活性与全身炎症的关系
补充资料:胆碱乙酰化酶
分子式:
CAS号:

性质:又称胆碱乙酰基转移酶。一种酶,催化胆碱和乙酰辅酶A转变为乙酰胆碱和辅酶A。乙酰胆碱是重要的神经递质。溴乙酰辅酶A、氯乙酰胆碱等能抑制胆碱乙酰化酶。

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