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1)  prostate specific
前列腺特异性
1.
Objective: To investigate the expression and significance of prostate specific antigen (PSA) and androgen receptor(AR) in extramammary Paget’s disease (EMPD).
目的:了解前列腺特异性抗原(prostate specific antigen,PSA)和雄激素受体(androgen receptor,AR)在乳房外Paget病(EMPD)中的表达及其意义。
2)  Prostate specific membrane antigen
前列腺特异性膜抗原
1.
Prostate specific membrane antigen expression of prostatic adenocarcinoma and the relationship between PSMA expression and histologic grade;
前列腺特异性膜抗原表达的临床意义
2.
Objective:To investigate the effects of treatment of prostate cancer by high intensity focused ultrasound(HIFU) on serum prostate specific membrane antigen(PSMA) and activation of cytotoxic T lymphocytes.
目的:研究超声聚能刀(HIFU)治疗前列腺癌对血清前列腺特异性膜抗原(PSMA)水平变化及特异性激活细胞毒性T淋巴细胞活性的影响。
3.
Objective: To screen and characterize the variable region gene about prostate specific membrane antigen(PSMA) of the Chinese Fab fragment,and to establish a new approach to researches on PSMA and prostate gene therapy.
目的:筛选、鉴定抗中国人前列腺特异性膜抗原(PSMA)的人源Fab抗体可变区的编码基因,为PSMA蛋白质生物学功能的研究及前列腺癌的基因治疗研究开辟新途径。
3)  prostate-specific antigen
前列腺特异性抗原
1.
Construction and expression of recombinant human prostate-specific antigen expression vector pPICZα-mPSA;
前列腺特异性抗原基因重组表达载体pPICZαC-mPSA的构建和表达(英文)
2.
The progression of prostate-specific antigen in diagnosis of prostate cancer;
前列腺特异性抗原在前列腺癌诊断中的应用进展
3.
Application of complexed prostate-specific antigen,total prostate-specific antigen and its ratio in the diagnosis of prostate cancer
复合前列腺特异性抗原、总前列腺特异性抗原及其比值在前列腺癌诊断中的应用
4)  prostatic specific antigen
前列腺特异性抗原
1.
Objective To investigate the expressions of prostatic specific antigen(PSA) mRNA in mononuclear cells of the peripheral blood in prostate cancer patients and controls and discuss its clinical significance.
目的:检测前列腺癌患者及对照者外周血单个核细胞前列腺特异性抗原(PSA)mRNA表达,并探讨其临床意义。
2.
Objective: To investigate the levels of prostatic specific antigen(PSA) in patients with chronic prostatitis.
目的 :研究慢性前列腺炎 (chronicprostatitis ,CP)中前列腺特异性抗原 (PSA)水平。
5)  prostate-specific membrane antigen
前列腺特异性膜抗原
1.
Construction of bicistronic DNA vaccine expressing prostate-specific membrane antigen and granulocyte-macrophage colony-stimulating factor and determination of its activity;
前列腺特异性膜抗原、粒细胞-巨噬细胞集落刺激因子双顺反子DNA疫苗的构建及其免疫活性的测定
2.
Molecular cloning of a complementary DNA encoding prostate-specific membrane antigen and its usage in detection of patients with prostatic carcinoma;
前列腺特异性膜抗原cDNA的克隆及用于临床前列腺癌的检测
3.
Objective To construct the tumor cells model expressing prostate-specific membrane antigen(PSMA) for the research of anti-tumor effect and immune mechanism about the DNA vaccine.
目的构建表达前列腺特异性膜抗原(PSMA)的肿瘤细胞模型,为基因疫苗的抑瘤效应研究及免疫机制的探讨提供实验材料。
6)  prostate-specific membrane antigen(PSMA)
前列腺特异性膜抗原
1.
Prostate cancer cells are known to secrete significant amounts of prostate-specific antigen(PSA),human glandular kallikrein 2(hK2) and prostate-specific membrane antigen(PSMA),which represents a target for selectively releasing an anticancer agent from a prodrug formulation.
前列腺癌细胞特异性地分泌大量的前列腺特异性抗原(PSA)、人腺激肽释放酶2(hK2)和前列腺特异性膜抗原(PSMA),设计合成被PSA,hK2和PSMA水解活化的前药,可以针对前列腺癌进行靶向治疗。
补充资料:周期性特异性药物


周期性特异性药物


仅能杀灭*细胞增殖周期中某一期癌细胞的抗癌药物。依其作用又分为两类:①作用于S期药物,如*羟基脲、*阿糖胞苷,甲氨蝶呤、巯基嘌呤、硫鸟嘌呤等。其中前两种药物特异性较高,主要干扰DNA合成,但因也能干扰 RNA的合成,可能起到一定的自限作用。临床上宜缓慢静滴或肌注给药。②作用于M期的药物,如长春新碱等。
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