The 8-iso-prostaglandin F2α(8-iso-PGF2α) levels in the renal tissue were determined by enzyme-linked immunosorbent assay(ELISA) and the superoxide dismutase(SOD) activity was detected by chemilumi-nescent analysis.

Objective: To detect the changes of 8-iso-prostaglandin F2α (8-ISO-PGF2α) in serum and the hippocampus and to observe the intervention effect of apigenin in immature rats exposing to intermittent hypoxic.

Objective:To investigat the plasma 8-iso-prostaglandin F2α(8-iso-PGF2α)and the serum C-reactive protein(CRP)levels in patients with chronic obstructive pulmonary disease(COPD),and also explore the pathogenesis of COPD.

8-iso-prostaglandin F2α and Type 2 Diabetes Mellitus;

Objective To evaluate the therapeutic effect of N-acetylcysteine(NAC) against myocardial ischemia-reperfusion injury during cardiopulmonary bypass(CPB) in infants with congenital heart disease(CHD),by exploring the chang of levels of plasma 8-iso-prostaglandin F2α(8-iso-PGF2α),in order to provide a new method for prevention and cure of the lipid peroxidation damage at CPB stage.

Objective To explore the changes of blood 8-iso-Prostaglandin F_(2a)(8-iso-PGF_(2a))content in different time after building-model and study its significance,and study the intervention effect of N-acetylcysteine(NAC) on it.

Changes and significances of 8-isoprostane in exhaled breath condensate in obstructive sleep apnea hypopnea syndrome

primary part The Investigation of Serum 8-Isoprostane, GSH-Px inPatients with Obstructive Sleep Apnea/hypopnea Syndrome Objective To investigate the expression of Serum 8-isoprostane, glutathioneperoxidase(GSH-Px) in patients with obstructive sleep apnea/hypopnea syndrome(OSAHS), and explore changes of oxidative stress in patients of OSAHS in vivo.

Objective To invesitgate the relationship between 8-isoprostane(8-iso-PG) level in exhaled breath condensates(EBCs) and severity of asthma and explore the role of 8-iso-PG in asthma evaluation and monitoring.