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1)  VIN [vɛ]
外阴上皮内瘤变
1.
The aim of this investigation was to study the expression of HIF-1αin vulvar squamous cell cancer,VIN,nonneoplastic epithelial disorder of skin (NNEDV)and normal skin in order to find their relation.
目前研究表明缺氧诱导因子的表达异常与血管生成有关,因此,本研究选取HIF-1α,CD34对正常外阴皮肤、外阴皮肤及粘膜上皮内非瘤样病变、外阴上皮内瘤变、外阴鳞癌组织进行研究,探讨HIF-1α在外阴癌前疾病和外阴癌变中的表达及与血管生成的关系。
2.
The aim of thisthesis was to study the expression of iNOS and eNOS in VSCC, VIN, NNEDV andnormal skin in order to find their relation.
本研究检测iNOS和eNOS在外阴正常皮肤、外阴上皮内非瘤样病变(NNEDV)、外阴上皮内瘤变(VIN)及外阴鳞癌(VSCC)中的表达,并以人原始造血细胞抗原(CD34)标记微血管内皮细胞,测量各组织的微血管密度(MVD),探讨iNOS和eNOS与外阴癌前疾病和外阴鳞癌的关系。
3.
Methods To establish 129/J mice model of VINⅠ-Ⅱby injected estradiol benzoate into the abdominal subcutaneous of 40 mice for 7 weeks.
目的外阴上皮内瘤变是发生于外阴上皮内的一组癌前病变,可进展为浸润性癌。
2)  vulvar intraepithelial neoplasia
外阴上皮内瘤变
1.
Relationship between development of vulvar intraepithelial neoplasia and infection of human papilloma virus;
外阴上皮内瘤变与人乳头状瘤病毒感染的相关性
2.
Objective: To clarify the role of mucin 1 (M VC1) and midkine(MK) in vulvar carcinogenesis by determining the expressions in vulvar intraepithelial neoplasia (VIN) and vulvar squamous cell carcinoma (VSCC) .
目的 :探讨黏蛋白 1(MUC1)和midkine(MK)在外阴上皮内瘤变 (VIN)和外阴鳞状细胞癌 (VSCC)中的表达及临床意义。
3)  Vulvar intraepithelial neoplasia
外阴上皮内瘤样病变
1.
Identification of human papillomavirus in vulvar intraepithelial neoplasia;
基于PCR的反向线杂交技术检测外阴上皮内瘤样病变中的HPV DNA
2.
Diagnosis and treatment and new pathologic classification of vulvar intraepithelial neoplasia
外阴上皮内瘤样病变新病理分类和诊治
4)  nonneoplastic epithelial disorders of vulva
外阴上皮内非瘤样病变
1.
Evaluation of curative effects of focused ultrasound treatment for nonneoplastic epithelial disorders of vulva;
聚焦超声治疗外阴上皮内非瘤样病变疗效评价
2.
A Clinical Analysis of Focused urtrasound therapy in Nonneoplastic epithelial disorders of vulva;
聚焦超声治疗外阴上皮内非瘤样病变的临床分析
3.
Objective:To evaluate the effects of high intensity focused ultrasound(HIFU) in treatment of 347 cases with nonneoplastic epithelial disorders of vulva.
目的:对347例外阴上皮内非瘤样病变患者进行聚焦超声治疗,评价其疗效。
5)  VIN [vɛ]
外阴上皮内瘤样病变
1.
Methods Materials: 30 cases of vulvar squamous carcinoma; 35 cases VIN (20 VINⅠ-Ⅱ, 15 VINⅢ); 40 cases of NNEDV (20 squmous cell hyperplasia,20 lichen sclerous) and 10 cases of norma.
目的 本研究通过免疫组化的方法,检测COX-2在外阴正常组织、外阴上皮内非瘤样病变、外阴上皮内瘤样病变及外阴鳞状细胞癌中的表达,并通过CD34标记的微血管分析COX-2表达与微血管密度的关系,旨在讨论COX-2与外阴癌前疾病、外阴鳞癌的关系及与血管生成的关系。
2.
Methods Expression of the FHIT and EGF was detected by immunohistochemical analysis in 20 normal vulvas and 22 vulvar intraepithelial neoplasias(VINS) as well as 60 primary vulvar carcinomas.
方法:用免疫组化SP法对20例正常外阴组织,22例外阴上皮内瘤样病变(VINS)以及60例外阴癌组织分别进行FHIT蛋白和EGF蛋白表达的检测。
6)  NNEDV
外阴上皮内非瘤样病变
1.
The aim of thisthesis was to study the expression of iNOS and eNOS in VSCC, VIN, NNEDV andnormal skin in order to find their relation.
本研究检测iNOS和eNOS在外阴正常皮肤、外阴上皮内非瘤样病变(NNEDV)、外阴上皮内瘤变(VIN)及外阴鳞癌(VSCC)中的表达,并以人原始造血细胞抗原(CD34)标记微血管内皮细胞,测量各组织的微血管密度(MVD),探讨iNOS和eNOS与外阴癌前疾病和外阴鳞癌的关系。
补充资料:子宫内膜上皮内瘤样病变


子宫内膜上皮内瘤样病变


EIN包括子宫内膜不同程度的不典型增生和原位癌。以前称之为子宫内膜不典型增生过长、腺瘤型增生过长、不典型腺瘤型增生过长、重度增生过长、腺型增生过长有细胞不典型及原位癌等。EIN的组织形态:腺细胞呈复层,排列失去极性,较大而不规则,有大而不规则的核仁、局部细胞质多而呈伊红色。病灶多为局部、多发性,可与正常、萎缩或各型增生过长相间存在。目前EIN名称尚未被广泛应用,仍多用子宫内膜不典型增生。至于子宫内膜原位癌的诊断至今尚无统一的定义。近年部分病理学家意见:“一个真正的内膜原位癌是腺体已有肿瘤性变化而无间质浸润。”而实际上在诊断时要肯定这样的病变相当困难。一般临床遇到EIN中至重度时,故其癌前病变常采用手术治疗,切除子宫。
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