1)  BL-CFC
BL-CFC
1.
To study the regulation of TGF-β1 on the development of hemangioblast, embryonic stem cell-derived blast forming cells (BL-CFC) were used as the model of hemangioblast in vitro.
胚胎干细胞来源的BL-CFC体外可分化产生造血和内皮细胞。
2.
5 days EBs differentiated from ES cells contain blast colony-forming cells (BL-CFC) that have bipotential of differentiation to hematopoietc and endothelial cells, thus functionally representing hemangioblast in vivo.
5天形成的拟胚体中可检测到blast集落形成细胞(blast colony-forming cell,BL-CFC),后者具有造血和内皮双向分化潜能,体外证明了成血-血管细胞的存在。
3.
BL-CFC is the first direct evidence, and the model has been applied extensively to investigate the regulatory mechanisms underlying development and differentiation of hemangioblast from embryonic stem cells.
1997年Keller等在小鼠胚胎干细胞建立的BL-CFC(blast-colony forming cell)是最早证实该细胞存在的模型,目前已广泛应用于血液血管干细胞的发育调控研究。
补充资料:cfc 112
CAS:76-12-0
分子式:C2Cl4F2
分子质量:203.83

中文名称:1,2-二氟四氯乙烷;氟里昂-112

英文名称:1,2-difluoro-1,1,2,2-tetrachloro-ethan;1,1,2,2-tetrachloro-1,2-difluoroethane;1,2-difluoro-1,1,2,2-tetrachloroethane;cfc 112;cfc-112;daiflon 112;daiflon s2;1,1,2,2-tetrachloro-1,2-difluoro-ethan

性状描述:高沸点;有类似樟脑气味的惰性液体。熔点25℃,沸点93℃,相对密度(25/4℃)1.6447,折光率(nD25)1.4130。


生产方法:六氯乙烷与氟化氢在催化剂五氯化锑存在下进行反应,反应产物经碱洗;水洗;分馏;提纯得三氟三氯乙烷,同时副产氟里昂112。

用途:用于生产致冷剂;气溶胶;推进剂;精密仪器清洗剂,可用作树脂中间体。还可用于生产治疗牛的肝蛭驱虫剂。用氟里昂112作原料制得甲氧氟烷,是一种新型的吸入全身麻醉药。
说明:补充资料仅用于学习参考,请勿用于其它任何用途。