1) PDC-E2 specific CTL
PDC-E2特异性CTL
1.
Functional analysis of HLA-A* 0201-restricted PDC-E2 specific CTLs in primary biliary cirrhosis;
原发性胆汁性肝硬化HLA-A* 0201限制性PDC-E2特异性CTL功能分析
2) specific CTL
特异性CTL
1.
The Comparison of inducing specific CTL by two methods of leukemia cell antigen loading of DCs and fusion of DCs with leukemia cells;
两种白血病细胞抗原负载DC的体外诱导特异性CTL应答的比较
2.
Investigaton of the relationship between cytotoxicity of specific CTL and HLA allotype;
特异性CTL胞毒作用与HLA型别关系探讨
3.
HBcAg-specific CTL response induced by PTD-HBcAg fusion protein to inhibit HBV replication in vitro
PTD-HBcAg融合蛋白经树突状细胞诱导特异性CTL抑制HBV的体外研究
3) Specific cytotoxic T lymphocyte
特异性CTL
1.
Induction of specific cytotoxic T lymphocytes and humoral immune response by MUC1 DNA vaccine in mice;
MUC1基因疫苗诱导小鼠特异性CTL和体液免疫应答
4) CTL responses
CTL特异性应答
5) tumor-specific CTL
肿瘤特异性CTL
1.
The cocultural system in vitro (CCS) was used in the present study to induce tumor-specific CTL by IL-18 in order to investigate the effects of various cell components of peripheral blood to prime and enhance the tumor-specific immune responses.
结果表明 ,在肿瘤抗原存在的条件下 ,CCS中rhIL 18能够诱导并促进CTL介导的肿瘤特异性杀伤效应 ;并且 ,在rhIL 18诱导肿瘤特异性CTL的过程中 ,rhIL 18、NK细胞、DC及T细胞均起着十分重要的作用 ,缺少任一组份 ,均对诱导肿瘤特异性CTL有明显差异 (P <0 0 1)。
补充资料:周期性特异性药物
周期性特异性药物
仅能杀灭*细胞增殖周期中某一期癌细胞的抗癌药物。依其作用又分为两类:①作用于S期药物,如*羟基脲、*阿糖胞苷,甲氨蝶呤、巯基嘌呤、硫鸟嘌呤等。其中前两种药物特异性较高,主要干扰DNA合成,但因也能干扰 RNA的合成,可能起到一定的自限作用。临床上宜缓慢静滴或肌注给药。②作用于M期的药物,如长春新碱等。
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