Progress of Simulating Construction for the Structure of Icosahedral Virus Capsids

The capsids of nearly all spherical viruses adopt icosahedral symmetry.

It was indicated that structural protein of icosahedral viruses capsid in fact take on various conformations.

Construction of a liver targeting gene transfer vector using hepatitis B virus envelope particles and assessment of its function;

Inhibitive effect of diphtheria toxin A under control of promoter of human-αfetoprotein gene(AFP-DTA) using hepatitis B virus envelope as gene transfer vector for hepatocarcinoma cells;

In order to construct an efficientHBV-based vector for targeting the liver, we get hepatitis B virus envelope through themethod ofβ-propiolactone.

Study on the new processing and technique of Chinese chestnut shelling with microwave;

Preparation and characterization of monoclonal antibodies against Norovirus capsid protein;

Expression of the fusion protein of dengue virus capsid protein C and staphylococcal nuclease in Escherichia coli;

Expression and self-assembly of dengue virus capsid protein;

Codon Optimization and Expression of Norovirus Capsid Proteins in Insect Cells;

Construction and Characterization of SHIV Carrying HIV-1 Capsid;

Expression of Matrix and Capsid Portein of Bovine Immunodeficiency Virus;

Cloning and expression of the coat protein gene of IHHNV in shrimp and its antiserum preparation;

Site-directed mutagenesis was performed at the codon 15 of the MS2 bacteriophage coat protein gene,which had been cloned to the virus-like particles expression vector containing non-self RNA fragment.

The analysis results of nucleotide sequences of their coat protein genes with those of other 2 TuMV isolates showed that they could be clustered into three groups.