Objective To clone Mouse Foxp3 gene(MFoxp3) and construct the prokaryotic expression vector of the protein,and to express and purify mouse Foxp3 fusion protein.

Foxp3 gene expression in rat allograft liver transplantation tolerance model;

Expression of CD4~+CD25~+ regulatory T cell and Foxp3 gene in systemic lupus erythematosus;

Changes of number of regulatory T cells in peripheral blood and expression of Foxp3 gene in pemphigus vulgaris;

Influence of Foxp3 gene-transferred CD4~+ CD25~- T cells on proliferation of allo T cells;

Objective: (1) To explore the relationship among CD4~+CD25~+ regulatory T cell, the level of IL-10 and TGF-β and the expression of FOXP3 mRNA levels of donor BM with GVHD in allogeneic hematopoietic stem cell transplantation(allo-HSCT).

Objective:To investigate the potential inhibiting ability to active lymphocytes proliferation and skin allograft rejection of the fusion protein of mouse forkhead box P3 combining with protein transduction domain(PTD-mFoxp3) in mice.

Multi-lineage potential of adipose tissue-derived stromal cells from green fluorescent protein transgenic mice;

Construction of transgenic mice expressing GFP and Embryo Cryopreservation;

The anti-Fas ligand treatment in HBsAg-transgenic mice with chronic hepatitis B;

In vivo micronuclei and gene mutation induced by DEN in the lacZ transgenic mouse;

Establishment of transgenic mouse model harboring hepatitis B virus x gene;

Production of transgenic mouse harboring full-length hepatitis G virus genome;