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1)  platelet-derived growth factor
血小板生长因子
1.
Role of platelet-derived growth factor in the pathogenesis of preeclampsia;
血小板生长因子与子痫前期发病的关系
2.
Effect of PLC-γ1 on cell proliferation induced by platelet-derived growth factor;
PLC-γ1对血小板生长因子介导的细胞增殖的影响
3.
Objective To study the role of platelet-derived growth factor (PDGF) in the etiology of pregnancy-induced hypertension (PIH), go step further to clarify the pathogenesis of PIH.
血小板生长因子(PDGF)是一类参与血管病变的血管活性多肽,是极强的生长促进因子及血管收缩剂,在高血压、冠心病、组织损伤等中有着极广泛的研究。
2)  PDGF
血小板生长因子
1.
PDGFBB STIMULATES DNA AND PROTEIN SYNTHESIS IN PULMONARY ARTERIAL SMOOTH MUSCLE CELLS OF RABBIT IN VITRO;
血小板生长因子(PDGF-BB)刺激体外培养兔肺动脉平滑肌细胞DNA和蛋白质合成
2.
Using the immortalized fibroblasts genetically deficient in PLC-γ1(PLC-γ1 -/- )to investigate the role of PLC-γ1in mobilization of intra-cellular Ca 2+ induced by platelet-derived growth factor(PDGF),we found in PLC-γ1 -/- cells,the mobilization of C.
应用无内源性PLC-γ1小鼠成纤维细胞株,观察在血小板生长因子PDGF作用下细胞内钙流的产生情况,发现缺失PLC-γ1的细胞与正常细胞都出现细胞内钙动员。
3.
To assess the effects of platelet growth factor (PDGF BB) on hypoxia induced pulmonary arterial remodelings, Sprague Dawley rat model with chronic hypoxia induced pulmonary arterial remodeling was established.
为了探讨血小板生长因子BB(PDGF-BB)在缺氧性肺血管结构重塑中作用,通过建立大鼠缺氧性肺血管重塑动物模型,运用原位杂交技术和免疫组织化学染色技术检测不同缺氧时期大鼠肺组织中原癌基因sismRNA和PDGF-BB蛋白表达。
3)  PLATELET-DERIVED GROWTH FACTOR/blood
血小板源生长因子/血液
4)  platelet-derived growth factor BB
血小板衍生生长因子BB
1.
Objective:To explore the relationship among vascular endothelial growth factor C(VEGF-C),platelet-derived growth factor BB(PDGF-BB),lymphangiogenesis and lymph node metastasis in human non-small cell lung cancer(NSCLC).
目的:探讨血管内皮生长因子C(VEGF-C)和血小板衍生生长因子BB(PDGF-BB)在非小细胞肺癌(NSCLC)中的表达与淋巴管生成和淋巴结转移的关系。
2.
Objective To investigate the intracellular calcium concentration alteration induced by platelet-derived growth factor BB(PDGF-BB) and the mechanism of ion flux in cultured glomerular mesangial cells.
目的 研究血小板衍生生长因子BB(PDGF-BB)引起的肾小球系膜细胞内游离钙浓度变化及其离子流动机制。
5)  platelet derived growth factor-BB
血小板衍生生长因子-BB
1.
Objective To explore the effects of platelet derived growth factor-BB(PDGF-BB)and basic fibroblast growth factor(bFGF)on alkaline phosphatase(ALP)activity in human periodontal ligament cells(hPDLCs)in vitro.
目的探讨血小板衍生生长因子-BB(PDGF-BB)和碱性成纤维细胞生长因子(bFGF)对人牙周膜(PDL)细胞碱性磷酸酶(ALPase)活性的影响。
6)  Platelet-derived growth factor
血小板衍生生长因子
1.
Prokaryotic expression and bioactivity of human platelet-derived growth factor B chain mature peptide;
人血小板衍生生长因子BB原核表达及生物学活性鉴定
2.
Expression and significance of platelet-derived growth factor and its receptor in renal interstitium of rats with UUO;
血小板衍生生长因子及其受体在梗阻性肾病大鼠肾间质中的表达
3.
Effect of 8-Br-cAMP and platelet-derived growth factor on E_2 excretion of granulosa cell from polycystic ovarian syndrome patients;
8-Br-cAMP和血小板衍生生长因子对多囊卵巢综合征患者颗粒细胞E_2生成的影响
补充资料:血小板衍生生长因子
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性质:platelet derired growth factor;PDGF 贮存于血小板α颗粒中的一种碱性蛋白质,是一些细胞,如纤维母细胞、平滑肌细胞、神经胶质细胞的促细胞分裂剂。包括PDGF-I和PDGF-II,二者所含蛋白质相同,仅糖苷含量各异,它们是由两个不同的多肽链由二硫键结合而成的二聚体,其中A链较大(PDGF-I中的A链为17 000,PDGF-II中的A链为15 000),B链较小(14 000)。由血小板纯化得到的PDGF为AB、BB双聚体,许多肿瘤细胞中的PDGF为AA双聚体。目前认为PDGF在伤口愈合、胆固醇与磷酯合成的调节、动脉粥样硬化等多种生理及病理过程中起重要作用。

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