Objective:To explore the role of efflux pump in drug resistance to fluoroquinolones in Stenotrophomonas maltophilia.

The exces-sive expression of active efflux pump gene is subscribed to the drugs active efflux of acinetobacter baumannii.

To explore the effect to the active efflux mechanism in Enterococcus and to detect the distribution and expression of active efflux pump gene emeA for the guidance of rational use of antibiotics and effective surveillance of nosocomial infections.

Distribution and expression of active efflux pump acrAB in clinical isolates of Shigella;

Initial Exploration of Drug Active Efflux Pump of Fluconazole-resistant Candida Albicans;

Conclusion The multi-resistance of Acinetobacter baumannii was related to the effect of efflux system.

Objective To evaluate the role of outer membrane protein (Omp) F-deficiency and active efflux in the accumulation of hydrophilic fluoroquinolones ciprofloxacin (CPLX) and lomefloxacin (LMLX) in resistant E.

To identify if there was the mechanism of active efflux in erythromycin resistant Streptococcus strains with mefA gene isolated from veterinary clinic,several erythromycin resistant strains with mefA gene,ermB gene and several susceptible strains were selected in this test.

Objective To study the effects of active efflux inhibitor on the activities of quinolones against staphylococcus aureus,and investigate the prevalence of active efflux-mediated staphylococcus aureus in our hospital.

Study of active efflux mechanism in staphylococcus aureus resistant to Quinolone;