1) cytotoxic drugs
细胞毒性药物
1.
Objective To understand nurses’ cognition of self-handling of cytotoxic drugs and to identify the effect of related training on the knowledge of self-handling of cytotoxic drugs in Hematology and Oncology Department.
目的了解护理人员对细胞毒性药物防护知识的掌握程度,评价安全防护知识集中培训的效果。
2.
Objective To investigate the impacts of cytotoxic drugs on APE/ref-1 expression in A549 cell, in order to find the potential relationship between APE/ref-1 and chemoresistance of NSCLC.
目的 研究细胞毒性药物对A549细胞APE/ref-1表达的影响,初步探讨APE/ref-1与NSCLC耐药性产生的相关性。
2) Cytotoxic drug
细胞毒药物
1.
This article analyzes drug-reduced occupational and environmental hazards of cytotoxic drugs in their manufacturing, storing, distribution and management in our country.
分析国内细胞毒药物生产、储运、使用及废弃物带来的职业和环境危害 ,建议制订有关管理办法 ,保护相关人员健康和环
3) cytotoxic drugs
细胞毒药物
1.
A survey of self-protection awareness of nurses contacting with cytotoxic drugs;
护士接触细胞毒药物自我防护意识的调查
2.
ObjectiveTo explore the clinical feature of pneumocystis carinii pneumonia(PCP) as a complication of chemo-therapy of corticosteroid and cytotoxic drugs for glomerulonephritis.
目的研究糖皮质激素联合细胞毒药物治疗肾小球肾炎并发卡氏肺孢子虫肺炎(PCP)的临床表现。
3.
OBJECTIVES Monitoring the concentration of the cytotoxic drugs in drug configured room in various work periods and areas.
目的监测细胞毒药物配置室中不同工作时段及不同区域的空气逸散的药物的浓度。
4) cytotoxic drug
细胞毒素类药物
6) hypoxic cytotoxins
乏氧细胞毒性物
1.
Nowadays, research on radiosensitizers includes conventional nitroimidazoles, hypoxic cytotoxins,nitric oxide donor agents, allosteric effectors of haemoglobin, metalloporphyrins and so on.
目前 ,放射增敏剂的研究包括传统硝基咪唑类化合物、乏氧细胞毒性物、一氧化氮供体、血红蛋白别构效应物和金属卟啉等 ,它们通过不同作用机制改善组织氧合状态或选择性杀死乏氧细胞 ,从而提高细胞对射线敏感性。
补充资料:细胞毒性药物
细胞毒性药物
cytotoxic drugs
即烷化剂(如环磷酰胺、氮芥等)。为抗肿瘤药物,它们的细胞毒作用主要在于烷化DNA分子中的鸟嘌呤或腺嘌呤等,引起单链断裂,双螺旋链交联,因而改变DNA的结构而损害其功能,妨碍RNA合成,从而抑制细胞有丝分裂。另外烷化剂又是免疫抑制剂,抑制抗原敏感细胞的活动,阻断免疫母细胞的出现,伸进小淋巴细胞的分解,使其数目减少。临床常用于治疗肿瘤、难治性肾病等。
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参考词条