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1)  tissue inhibitor of metalloproteinase
金属蛋白酶组织抑制剂
1.
Objective To investigate the expressions of endothelin 1(ET 1), matrix metalloproteinase 3(MMP 3) and tissue inhibitor of metalloproteinase 1(TIMP 1) in human glomeruli and the related significance.
目的 研究内皮素 1(Endothelin 1,ET 1)、基质金属蛋白酶 3 (Matrixmetalloprotevnase 3 ,MMP 3 )、金属蛋白酶组织抑制剂 1(Tissueinhibitorofmelalloproteinase ,TIMP 1)在人肾小球中的表达变化及意义。
2)  tissue inhibitor of metalloproteinases
金属蛋白酶组织抑制剂
1.
A Study on the Roles of Tissue Inhibitor of Metalloproteinases (Doxycycline) on Human Colorectal Cancer Bearing Nude Mice;
金属蛋白酶组织抑制剂(多西环素)对大肠癌裸鼠移植瘤的影响研究
2.
Objective: To investigate the effect of hypoxia on the mRNA expression of tissue inhibitor of metalloproteinases (TIMPs) in breast carcinoma cell line (MDA-231) and the effect of basil polysaccharide (BP) on the expression of TIMPs.
目的:探讨低氧对人乳腺癌细胞株MDA-231金属蛋白酶组织抑制剂(TIMPs)mRNA表达的影响,以及罗勒多糖(basilpolysaccharide,BP)对TIMPs的作用。
3.
Tissue inhibitor of metalloproteinases can inhibit the activity of MMPs,so the using of TIMPs can be a new method to treat the ischemic cerebrovascular diseases.
大脑中动脉闭塞/再灌注(MCAO/R)实验动物模型研究显示,脑缺血/再灌注时,基质金属蛋白酶(MMPs)表达异常,提示其于脑缺血再灌注损伤有关,金属蛋白酶组织抑制剂(TIMPs)可特异性抑制MMPs的活性,从而有望成为治疗缺血性脑血管病的新手段。
3)  Tissue Inhibitors of Metalloproteinases
金属蛋白酶组织抑制剂
4)  Tissue inhibitor of matrix metalloproteinase
金属蛋白酶组织抑制剂
1.
Objective:To investigate the relationship between the expressions of matrix metalloproteinase-2 (MMP-2) and tissue inhibitor of matrix metalloproteinase-2(TIMP-2) mRNA and clinicopathologic characteristics of patients with ovarian malignant tumor.
目的 :探讨基质金属蛋白酶 - 2 (MMP- 2 )及基质金属蛋白酶组织抑制剂 - 2 (TIMP- 2 )在卵巢肿瘤中的表达及与卵巢恶性肿瘤临床病理特征和预后的关系。
5)  TIMP
金属蛋白酶组织抑制剂
1.
Objective:To determine the effect of acitretin on MMP-2 and TIMP-2 and to explore its treatment mechanism in the patients with psoriasis vulgaris.
目的:确定基质金属蛋白酶-2(MMP-2)及金属蛋白酶组织抑制剂-2(TIMP-2)在寻常型银屑病发病中的作用及阿维A对其的调节作用。
2.
Matrix metalloproteinases(MMP) and Tissue Inhibitor of metalloproteinases(TIMP) can regulate the degradation and synthesis of extracellar matrix(ECM), and participate in many physiogical and pathological processes in vivo.
基质金属蛋白酶 (MMP)和金属蛋白酶组织抑制剂 (TIMP)调节细胞外基质 (ECM)的分解与合成 ,参与体内多种生理病理过程。
6)  tissue inhibitor of metalloproteinase
组织金属蛋白酶抑制剂
1.
Tissue inhibitor of metalloproteinases(TIMPs)are the natural repressor of MMPs,the ratio between MMPs and TIMPs may be a significant target to reflect the activity and prognosis of RA.
组织金属蛋白酶抑制剂(TIMPs)是MMPs的天然抑制物,MMPs/TIMPs两者比例可作为反映疾病活动程度及预后的重要指标。
2.
Aim To investigate the mRNA levels of tissue inhibitor of metalloprot einase-1(TIMP-1),tissue inhibitor of metalloproteinase-2 (TIMP-2) in rat car diac fibroblasts by multiplex reverse transcription-polymerase chain reaction ( RT-PCR).
目的通过建立多重反转录聚合酶链反应(RT-PCR)方法,旨在测定大鼠心肌成纤维细胞组织金属蛋白酶抑制剂-1(TIMP-1)、组织金属蛋白酶抑制剂-2(TIMP-2)的mRNA水平。
补充资料:金属蛋白酶抑制剂
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性质:一类组成结构中含有一个或一个以上金属离子的蛋白酶,凡能抑制此类蛋白酶又不使酶蛋白变性的物质,都属于金属蛋白酶抑制剂。如,由田无链霉菌MD706-Y4产生的磷酰胺素(phosphoramidon),由马组链霉菌产生的塔罗肽(talopeptin)等都是金属蛋白酶抑制剂。

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