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1)  Chronic nerve defect
陈旧性神经缺损
2)  obsolete injury of sciatic nerve
陈旧性坐骨神经损伤
1.
Effect of obsolete injury of sciatic nerve on the content of NO、NOS activity and apoptosis of myocytes in rats gastrocnemius;
陈旧性坐骨神经损伤对大鼠腓肠肌组织一氧化氮、一氧化氮合酶和细胞凋亡的影响
3)  Long-term denervation
陈旧性损伤
4)  economic obsolescence
经济性陈旧
5)  nerve defects
神经缺损
1.
Improvement of preparative method of acellular nerve allograft and its effect on bridging of peripheral nerve defects;
化学去细胞同种异体神经制备的改良及桥接周围神经缺损效果
2.
Comparing the regeneration of sciatic nerve defects repaired after different predegeneration time in rats;
大鼠坐骨神经缺损后不同时间修复的效果比较
3.
Background: The treatment of peripheral nerve injury is a tough problem clinically, in which two crucial problems should be solved: the repair of nerve defects and neurotropic reinnervation of the nerve fibers.
为了最大限度地去除异体神经免疫原性物质,同时较完好地保存神经内部结构和细胞外基质的活性成分,本课题对化学去细胞神经的制备方法进行了改良,并修复大鼠坐骨神经缺损,评价其再生效果。
6)  nerve gap
神经缺损
1.
Objective To study the feasibility to repair the peripheral nerve gap with tissue engineering scaffold complex that is composed of medical biodegradable material agarose hydrogel and nerve growth factor (NGF).
目的探讨壳聚糖与琼脂糖水凝胶载体及外源性神经生长因子联合制成组织工程神经支架复合体修复大鼠周围神经缺损的可行性。
2.
Methods:The decellularized scaffolds prepared by using lyolecithin,DNase and RNase to treat the canine sciatic nerves were compounded with bone marrow derived neural tissue-committed stem cells via microinjection to creat the tissue engineered nerve,and thereby bridge the mouse sciatic nerve gap.
方法:将骨髓神经组织定向干细胞(NTC-SCs)种植于犬坐骨神经脱细胞神经支架,构建组织工程化神经,桥接缺损的大鼠坐骨神经,检测所构建生物化组织工程神经中骨髓NTCSCs的增殖、分化及神经性基因表达,观察该神经移植到体内后的细胞增殖、分化及对神经缺损功能的修复。
补充资料:陈旧性会阴Ⅲ度裂伤修补术


陈旧性会阴Ⅲ度裂伤修补术


会阴Ⅲ度裂伤为会阴裂伤中最严重者,常见于难产手术损伤或胎儿过大。儿头娩出时保护会阴不力所致。即肛提肌、阴道筋膜,肛门括约肌甚至直肠下段均有损伤而撕裂,以致大便失禁及不能完全控制排气。如果修补手术不在产后立即进行者称之为陈旧性会阴Ⅲ度裂伤修补术。术前准备:术前3日少渣饮食,每天用1∶5000高锰酸钾溶液坐浴1~2次,每晚灌肠1次。术前3日口服新霉素等药物控制肠道细菌。手术前晚清洁灌肠,麻醉,骶管麻醉,手术步骤:①认真检查裂伤情况及解剖关系。用两把鼠齿钳暴露裂伤边缘,沿裂伤边缘切开阴道黏膜,见阴道壁与直肠的分界,分离阴道壁与直肠黏膜,并向两侧分离阴道壁,暴露直肠及肛门扩约肌的两侧断端处,剪去直肠裂缘瘢痕组织。②缝合直肠用000可吸收线间断及连续缝合直肠壁,一般不透过直肠黏膜,亦可穿透黏膜,把结打在肠腔内;③缝合肛门括约肌,用鼠齿钳自两侧凹陷处夹取肛门括约肌断端,并向中线靠拢,用丝线作“8”字缝合。此时,肛门周围皮肤即皱缩呈环状。④缝合肛提肌,1号铬肠线间断缝合,⑤修剪阴道黏膜后1号肠线缝合阴道黏膜。⑥缝合皮肤和皮下组织。术后处理同会阴Ⅲ度裂伤。无渣饮食控制大便5天,以利伤口愈合。
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