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1)  Gerbils
蒙古沙鼠
1.
Method Gerbils were randomly divided into sham group,global ischemia group and global ischemia treated with Yangxueqingnaokeli group.
目的探讨养血清脑颗粒对蒙古沙鼠全脑缺血再灌注后的神经保护作用。
2.
Animal Groups:Fifty healthy male Mongolian gerbils,devided into fourgroups:Normal Group (n=5); Sham Operation Group (n=5); Ischemia Reperfusion Group (I/R) (n=20); Minocycline Intervention Group (MI/R) (n=20); I/R Group and MI/R Group are devided into four subg.
方法: (1)动物分组:健康雄性蒙古沙鼠50只,随机分为正常对照组、假手术组、缺血再灌注组(I/R)、美满霉素干预组(MI/R);观察在脑缺血再灌注后6h、1d、3d、7d的各相应时间点Hsp22及c-fos的表达; (2)模型制作:对照组沙鼠予以夹闭双侧颈总动脉10min后再灌注;假手术组沙鼠仅分离双侧颈总动脉不予以夹闭;美满霉素干预组于缺血再灌注前一天腹腔注射美满霉素(45mg/kg。
3.
ObjectiveTo explore the expression and the protective mechanisms of heat shock protein 27 (HSP27) and Insulin-like growth factor-1 (IGF-1) in brain tissue following cerebral ischemic reperfusion in Mongolian gerbils and whether they are correlative.
方法(1)动物分组:健康雄性蒙古沙鼠30只,随机分为正常对照组、假手术组、缺血再灌注组(I/R);观察在脑缺血再灌注后6h、1d、3d、7d的各相应时间点HSP27及IGF-1的表达;(2)模型制作:对照组沙鼠予以夹闭双侧颈总动脉10min后再灌注;假手术组沙鼠仅分离双侧颈总动脉不予以夹闭,然后建立缺血再灌注模型;(3)HE染色观察脑组织的病理变化;(4)免疫组织化学染色观察HSP27和IGF-1的表达情况;(5)所有统计分析均用SPSS 15。
2)  Mongolian gerbil
蒙古沙鼠
1.
Establishment of a Mongolian gerbil model infected steadily with Helicobacter pylori;
蒙古沙鼠感染幽门螺杆菌后的胃部病理学变化研究
2.
Objective To investigate the therapeutical effects of Yangxueqingnaokeli(YXQNKL) on global ischemia reperfusion injury in Mongolian gerbils.
目的探讨蒙古沙鼠全脑缺血再灌注后养血清脑颗粒(Yangxueqingnaokeli,YXQNKL)的治疗作用。
3.
Objective To analyze the mRNA expressions of INF-γ, IL-4 and IL-12p40 in the gastric mucosa of Mongolian gerbil infected of H.
目的通过比较幽门螺杆菌(Helicobacterpylori,Hp)感染蒙古沙鼠前后胃粘膜INF-γ、IL-4及IL-12p40mRNA水平的变化,确定Hp感染在蒙古沙鼠胃粘膜诱发的免疫应答方式。
3)  Mongolian gerbils
蒙古沙鼠
1.
Comparative proteomics analysis of Helicobacter pylori after adaptive colonization in Mongolian gerbils;
幽门螺杆菌适应性定植蒙古沙鼠前、后的蛋白质组学研究
2.
~(13) Curea breath test for the detection of Helicobacter pylori infection in Mongolian gerbils;
~(13)C-尿素呼气试验在蒙古沙鼠幽门螺杆菌感染检测中的应用
3.
Objective To establish and evaluate the animal model of nonalcoholic fatty liver disease in Mongolian gerbils.
目的初步建立并评价蒙古沙鼠非酒精性脂肪性肝病模型。
4)  Mongolian gerbil
蒙古沙土鼠
1.
Long-term infection with Helicobacter pylori in Mongolian gerbils;
幽门螺杆菌长期感染蒙古沙土鼠腺胃模型的建立及评价
2.
In addition,thirty Mongolian gerbils also used.
方法在布氏肉汤的基础上设计了4种Hp再生培养基,对Hp螺旋体、原生质体及球形体进行体外培养;同时采用30只蒙古沙土鼠(Mongolian gerbil)进行体内感染定植实验,对感染小鼠胃粘膜进行Hp定量培养和组织学检测。
3.
Objective Inhibitory effect of egg-yolk antibody on experimental Helicobacter pylori(Hp) infection in Mongolian gerbil was observed as soon as egg-yolk antibody against Hp was prepared.
目的在成功研制出抗幽门螺杆菌(Hp)卵黄抗体的基础上,利用蒙古沙土鼠作为实验动物,观察抗Hp卵黄抗体对Hp感染的防治作用。
5)  Mongolian gerbil IgG
蒙古沙鼠IgG
6)  Mongolian gerbils
蒙古沙土鼠
1.
Establishing Mongolian gerbils models of gastritis and peptic ulcer by long-term infection with Helicobacter pylori;
幽门螺杆菌长期感染蒙古沙土鼠导致胃炎、胃溃疡的实验研究
2.
Methods: The Mongolian gerbils of spleen deficiency induced by reserpine were inoculated with HpSS1 to establish the Mongolian gerbil model of spleen deficiency and to detect the gastric mucosal inflammation and Hp infection.
目的 :建立脾虚蒙古沙土鼠感染幽门螺杆菌 (Hp)动物模型 ,验证该模型出现的病理改变及 Hp定植情况。
3.
pylori,which was from salt pork and human gastric mucosa in Zhuanghe high risk of gastric cancer, infected Mongolian gerbils was used,we observed the proliferation of salt pork-derived H.
目前认为蒙古沙土鼠是最理想的研究H。
补充资料:科素亚 ,氯沙坦钾,氯沙坦, 芦沙坦, 洛沙坦
药物名称:洛沙坦

英文名:Losartan

别名: 科素亚 ,氯沙坦钾,氯沙坦, 芦沙坦, 洛沙坦
外文名:Losartan, Cozaar, Novartis
成分: 氯沙坦钾
适应症: 高血压。
用量用法:
通常剂量为50mg,qd,治疗3-6周后达到最大抗高血压效应。在部分病人中,每天剂量可增加到100mg。血容量不足的病人(例如应用大量利尿剂)起始剂量应该为25mg,qd。
禁忌: 儿童,妊娠和哺乳妇女。
不良反应:
轻微而短暂的头晕,剂量相关性体位性低血压。罕见皮疹、荨麻疹,血管神经性水肿(包括面、唇和/或舌肿胀)。腹泻及偏头痛。偶有高血钾,罕见ALT升高。敏感个体和动脉狭窄的病人可出现肾功能异常。
注意事项: 血容量不足的病人应先补充血容量,减少起始剂量。有肝功能损害病人应使用较低剂量。
规格: 片剂 50mg x 7片。


类别:抗高血压药
说明:补充资料仅用于学习参考,请勿用于其它任何用途。
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