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1)  drug-resistance gene
抗药基因
1.
Objective To study the drug-resistance gene carried by clinically isolated Pseudomonas aeruginosa and its relation to and level of resistance to disinfectants.
目的研究临床分离的铜绿假单胞菌携带的抗药基因情况及其与消毒剂的抗性关系和水平。
2.
Objective To study the drug-resistance gene carried by a few clinically isolated pathogenic bacteria and its level of resistance to povidone iodine.
目的研究几种临床分离病原菌抗药基因携带情况及其对聚维酮碘的抗力水平。
2)  Host-plasmid balanced lethal system
抗药性基因
3)  The multidrug resistance gene(pfmdr1)
多药抗性基因(pfmdr1)
4)  Resistant genes
耐药基因
1.
Detection of resistence to erythromycin and related resistant genes in streptococcus pneumoniae strains;
儿童肺炎链球菌分离株红霉素耐药性与相关耐药基因研究
2.
Analysis of enterococcal antimicrobial resistance and detection on antibiotics-resistant genes in children
儿童肠球菌耐药性分析和部分耐药基因检测
3.
Resistant genes encoding β-lactamases,aminoglycoside modifying enzymes and antiseptic resistance were detected by PCR amplification and verified by DNA sequencer.
结论临床分离的铜绿假单胞菌已携带多种耐药基因。
5)  resistance gene
耐药基因
1.
Analysis of drug resistance genes in extended spectrum β-lactamases producing Escherichia coli;
产超广谱β-内酰胺酶大肠埃希菌耐药基因分析
2.
Disinfectant-sulfadiazine Resistance genes in Escherichia coli Isolated from Elderly Wards
老年病区大肠埃希菌分离株消毒剂-磺胺耐药基因携带的研究
3.
Objective: To understand the resistance gene spectrum and genetics characteristics of Klebsiella pneumoniae(Kpn) producting ESBLs.
目的:了解产ESBLs肺炎克雷伯菌的耐药基因谱及其遗传学特征。
6)  Drug-resistant gene
耐药基因
1.
Analysis on drug-resistant gene of CTX-M extended-spectrum β-lactamase-producing Escherichia coli;
产ESBLs大肠埃希菌CTX-M型耐药基因分析
2.
Detecting drug-resistant genes from twelve gram-negative bacteria;
12株产β-内酰胺酶革兰阴性杆菌的耐药基因检测
3.
Drug-resistant gene,integron,and Tn21/Tn501 transposon were analyzed using polymerase chain reaction(PCR).
目的了解鲍氏不动杆菌(ABA)耐药基因和整合子、Tn21/Tn501转座子存在状况及菌株亲缘性。
补充资料:抗药基因
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性质:赋予宿主细胞对抗菌物质有耐受性的一类基因。通常由基因突变产生,如链霉素能与敏感菌株的核蛋白体30S小亚基结合,抑制细菌蛋白质合成。但是接触一定时间后,可因基因突变产生结构改变了的核蛋白体,使链霉素不能与之结合而失效。抗药基因还包括质粒所携带的抗药基因,常常是为特异分解此药物的酶编码的基因。带有抗药基因的质粒也称R因子或R质粒。R因子除能遗传子代外,还能通过噬菌体转导和细菌间的接合传布而产生新的耐药菌株。此外,耐药菌株溶解后释出的DNA还可重组进入敏感菌染色质中。

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