Methods:Protection of 4R-hydroxyl-L-proline(1)with p-nitrobenzylchloroformate gave the N-protected 4R-hydroxyl-L-proline(3),the carboxyl group of which was activated with i-propanylchloroformate;then aminolysis of the mix-anhydride with p-nitrobenzyl-m-aminobenzoate(11)gave compound 4.

(3S)-(+)-3-Mercapto-1-p-nitrobenzyloxycarbonylpyrrolidine,the main intermediates of Carbapenem RS-533 and its isomers,was synthesized through five-step reactions starting from L-hydroxyproline.

The present work aimed at development of a macroporous strongly acidie ion exchange resin,possessing an appropriate pore structure for ion-exchange-chromatographic purification of L-hydroxyproline.

The novel Pro/SBA-15 catalyst was prepared using SBA-15 zeolite as the support to immobilize L-proline(Pro) derivatives,which was synthesized from 4-hydroxy-L-proline.

Coordination Mechanism and Antioxidant Activity of L-hydroxyproline Zinc(Ⅱ);

Determination of L-hydroxyproline in milk powder by P-dimethylaminobenzaldehyde spectrophotometry

A new stationary phase was synthesized for chiral-ligand-exchange chromatography by treating the monodisperse poly(glycidylmethacrylate-co-ethylenedimethacrylate)particles with L-hydroxyproline.

Extraction Mechanism and Property of Phenyl Alanine with n-Octyl-L-hydroxyproline;