说明:双击或选中下面任意单词,将显示该词的音标、读音、翻译等;选中中文或多个词,将显示翻译。
您的位置:首页 -> 词典 -> 乏氧诱导因子-1α
1)  hypoxia inducible factor-1α
乏氧诱导因子-1α
1.
Objective To investigate the expression of hypoxia inducible factor-1α(HIF-1α)and microvessels density(MVD),and further to evaluate the correlation between them.
目的观察乏氧诱导因子-1α(HIF-1α)和微血管密度(MVD)在S180肉瘤中的表达水平,并探讨两者间的相关性。
2.
Methods:A549 cell line(human lung adenocarcinoma) was cultured under hypoxic atmosphere(2% O_2) for 24 h,the expression of hypoxia inducible factor-1α、P-gp and P53 protein was detected by immu.
方法:乏氧条件下(2%O2)人肺腺癌细胞株A549体外培养24 h,免疫组化法检测乏氧诱导因子-1α(H IF-1α)、P-糖蛋白(P-gp)和P53蛋白的表达;MTT法检测乏氧条件下A549细胞在多柔比星作用下的存活率;应用流式细胞仪检测细胞凋亡。
3.
Objective To investigate the correlation between the expression of DNA-dependent protein kinase (DNA-PK) and hypoxia inducible factor-1α (HIF-1α) induced by irradiation in hypoxic HeLa cell and the modulatory mechanism.
目的初步探讨辐射效应诱导下乏氧人宫颈癌细胞系HeLa细胞乏氧诱导因子-1α(HIF-1α)和DNA依赖蛋白激酶(DNA-PK)表达相关性及其调控机制。
2)  HIF-1α
乏氧诱导因子-1α
1.
Effects of silencing HIF-1α gene by RNA interference on Taxol-induced apoptosis of human esophageal squamous cell line EC9706;
RNA干扰沉默乏氧诱导因子-1α对紫杉醇诱导食管鳞癌EC9706细胞凋亡的影响
2.
Construction of RNAi adenoviral shuttle vector targeting both HIF-1α and survivin synchronously
靶向乏氧诱导因子-1α和生存素基因的RNA干扰腺病毒穿梭载体的构建
3.
In order to investigate the anti-tumor effect of RNA interference silencing HIF-1α and Survivin genes combined with X-ray irradiation on hypoxic SMMC-7721 cells in vitro, we detected mRNA and protein expression of HIF-1α and Survivin genes in hypoxic SMMC-7721 cells after transfection with pGenesil-Survivin-HIF carried by liposome by RT-PCR and Western blot respectively.
为探讨RNA干扰(RNAinterference,RNAi)沉默乏氧诱导因子-1α(Hypoxia induced factor 1α,HIF-1α)和生存素(Survivin)基因联合X射线照射对乏氧人肝癌细胞SMMC-7721的体外抑瘤效应,利用双靶向HIF-1α和Survivin基因载体,采用阳离子脂质体介导法转染SMMC-7721细胞,经乏氧培养36h后,分别以RT-PCR和Western blot法检测HIF-1α和Survivin基因的mRNA及其蛋白表达,分别以四甲基偶氮唑盐(MTT)法和流式细胞术检测细胞存活分数及细胞凋亡。
3)  Hypoxia inducible factor 1α
乏氧诱导因子-1α
4)  HIF-1α
乏氧诱导因子1α
1.
Objective To evaluate the feasibility of HIF-1α(hypoxia induce factor-1α)expression and SPECT image with ~(99)Tc~m-EC-MNZ (~(99)Tc~m-EC-metronidazaole) in detecting tumor hypoxia,and to observe the correlation between these two methods.
目的探讨肿瘤乏氧诱导因子1α(HIF1α)表达及乏氧显像剂99TcmEC甲硝唑(metronidazole,MNZ)SPECT显像对检测肿瘤乏氧(缺氧)程度的可行性,以及两种检测方法的相关性。
5)  C-erbB-2·Hypoxia inducible factor-1
C-erbB-2·乏氧诱导因子-1α
6)  Hypoxia-inducible factor-1α
缺氧诱导因子-1α
1.
Expression of hypoxia-inducible factor-1α and vascular endothelial growth factor in the retina of diabetic rats;
糖尿病大鼠视网膜中缺氧诱导因子-1α和血管内皮生长因子表达的研究
2.
Effects of Chinese herbs for replenishing qi and resolving stagnation on hypoxia-inducible factor-1α and vascular endothelial growth factor in granulation tissue of skin ulcers in rats with diabetes;
益气化瘀中药对糖尿病皮肤溃疡大鼠缺氧诱导因子-1α和血管内皮细胞生长因子的影响
3.
Expression of hypoxia-inducible factor-1α in endometriosis;
缺氧诱导因子-1α在子宫内膜异位症的表达及意义
补充资料:α,α,α,α',α',α'-六氯对二甲苯
分子式:C8H4Cl6
分子量:312.84
CAS号:68-36-0

性质:白色针状或粉末状结晶。熔点108-110℃。溶于二甲苯、石油醚、乙醇、植物油,不溶于水。无味,有特殊臭味,遇光、碱会缓慢分解而呈酸性。

制备方法:以混二甲苯为原料,先用98%硫酸磺化,使间二甲苯生成间二甲苯磺酸盐。从磺化反应物中分离出含邻、对二甲苯的油层,水洗、干燥,减压蒸馏出邻、对二甲苯。间二甲苯磺酸盐经水解可得副产品间二甲苯。由邻、对二甲苯经氯化即得1,4-双(三氯甲基)苯:在反应锅中投入邻、对二甲苯,再加入过氧化苯甲酰和三乙醇胺。加热到70℃后,在光照射下导入氯气,于70-80℃反应6h,再升温至100-120℃继续反应,至反应液相对密度达到1.560-1.580(65℃),即为反应终点,停止通氯,减压脱除余氯。降温至5℃,过滤,洗涤得粗品,重结晶,活性炭脱色得成品。

用途:抗血吸虫病药物。对肝吸虫病、阿米巴原虫病、疟疾以及肠道线虫有一定疗效。但对神经系统的不良反应较多见,且延迟反应持续较久。

说明:补充资料仅用于学习参考,请勿用于其它任何用途。
参考词条