The synthesis routes and research advance of plasma lipid regulators: pitavastatin calcium were reviewed with 21 references.

This method is improved for preparing the intermediate of pitavastatin calcium by the reaction of L-(-)-malic acid through methyl esterification,selective reduction,trityl protection,Claisen condensation,stereoselective reduction,ketalization,deprotection of trityl and Swern oxidation.

A RP-HPLC method was established for the determination of the related substances in pitavastatin calcium.

Improvement in synthesis of the intermediate of pitavastatin;

Determination of pitavastatin in human plasma by liquid chromatographytandem mass spectrometry;

Effect of different dosages of pitavastatin on blood flow recovery in ischemic limbs of mice;

Pitavastatin enhances angiogenesis and perfusion in a murine model of limb ischemia;

Effect and Mechanism of Pitavastatin in Therapeutic Angiogenesis Study;

AIM To evaluate the effects of high fat diet on the pharmacokinetic profiles of pitavastatin and its metabolite,pitavastatin lactone,in Chinese male healthy volunteers.

Tne effect of cholesterol-lowering therapy with atorvastatin on endothelium-dependent relaxing function in patients with hypercholesterolemia;

Effects of Atorvastatin on Vascular Cognitive Impairment Combined with Hyperlipidemia

The effects of Atorvastatin on recurrence of ischemic cerebrovascular disease