1) multiple myeloma/compiications
多发性骨髓瘤/并发症
2) multiple myeloma
多发性骨髓瘤
1.
An analysis of ocurrence and prognosis related factors of renal dysfunction in patients with multiple myeloma.;
多发性骨髓瘤肾功能损害及预后相关因素研究
2.
The influence of vascular endothelial growth factor on secretion of interleukin-6 of bone marrow stromal cells in multiple myeloma;
VEGF对多发性骨髓瘤骨髓基质细胞分泌IL-6的影响
3.
Effects of arsenic trioxide on the biological characteristics of multiple myeloma cell line RPMI8226;
三氧化二砷对多发性骨髓瘤细胞生物学特性的影响
3) Multiple Myeloma(MM)
多发性骨髓瘤
1.
Objective:To investigate the application of immunoglobulin heavy chain(IgH) gene rearrangement in the diagnosis and therapy of multiple myeloma(MM).
目的:探讨免疫球蛋白重链(IgH)基因重排在多发性骨髓瘤(MM)患者治疗过程中监测的临床意义。
2.
Objective To explore whether there is any association between multiple myeloma(MM)and the infection of Borna disease virus(BDV).
目的探讨Borna病病毒(BDV)感染与人类多发性骨髓瘤(MM)发病的关系。
3.
Objective To estimate the prevalence of depression and anxiety in patients with multiple myeloma(MM)and to analyze the possible impact factors.
目的评估多发性骨髓瘤(MM)患者伴抑郁、焦虑情绪的发生率,并分析其相关的影响因素。
4) MM
多发性骨髓瘤
1.
Detection and clinical significance of serumβ_2-MG、CRP level in MM;
多发性骨髓瘤患者血清β_2-M、CRP水平的测定及临床意义
2.
Objective: Aim Discussing the clinical characters,diagnosis,therapies,prognosis and some concerning factors of MM,discussing the reason of the error diagnosis,concluding the experience of the diagnosis and therapies.
目的:探讨多发性骨髓瘤的临床特点、诊断、治疗及预后等相关因素,探讨误诊的原因,总结诊断和治疗的经验。
3.
Methods Monocytic cells of bone marrow samples from 24 cases with acute lymphoblastic leukemia(ALL),15 cases with multiple myeloma(MM),26 cases with non-Hodgkins lymphoma(NHL),4 cases with chronic lymphocytic leukemia(CLL),4 cases with Hodgkins lymphoma(HD) and 16 healthy persons were measured by immunological fluores.
方法 用免疫荧光方法检测 2 4例急性淋巴细胞白血病 (acutelymphoblasticleukemia ,ALL) ,15例多发性骨髓瘤 (multi plemyeloma ,MM) ,2 6例非霍杰金氏淋巴瘤 (non Hodgkinslymphoma ,NHL) ,4例慢性淋巴细胞白血病 (chroniclymphocyticleukemia ,CLL) ,4例霍杰金氏淋巴瘤 (Hodgkinslymphoma)及 16例正常人造血干细胞CD+ 3 4细胞表面CD5 4的表达。
5) multiple myeloma (MM)
多发性骨髓瘤
1.
Objective To determinate the concentrations of angiognic factors of bone marrow (BM) in multiple myeloma (MM) patients at different clinical stage,to analyze the relationships between angiogenesis and clinical status.
目的测定不同临床阶段多发性骨髓瘤(MM)患者骨髓中血管新生因子的水平,分析其与疾病-临床分期之间的关系。
2.
1dele ted in multiple myeloma (MM)patients,the expressed sequence ta gs(ESTs )which represent the novel gene in thi s region were obtained by bioinformatics analysis,then its expression was detected by semi-quantitative reverse tran-scription -polymerase chain reaction(RT-PCR).
为克隆位于多发性骨髓瘤(multiplemyeloma,MM)患者染色体13q14。
3.
Aim:To improve differential diagnosis by imaging(X-ray and CT) between multiple myeloma (MM) and metastatic tumor of bone.
目的：为了提高对多发性骨髓瘤（ Ｍ Ｍ） 和骨转移瘤的影像学（ Ｘ 线、 Ｃ Ｔ） 的鉴别诊断水平。
6) Mutiple myeloma
多发性骨髓瘤
1.
Suppression effect of supernatant from Mutiple myeloma cells RPMI8226 on the early stage of osteoblast differentiation;
多发性骨髓瘤细胞株RPMI8226上清液抑制成骨细胞早期分化
2.
Objective To compare the morphology and phenotype differences of dendritic cells DCs from mutiple myeloma(MM) patients and normal donors and provide the evidence of initiative and specific immunotherapy of MM.
目的 比较多发性骨髓瘤 (MM)来源的树突状细胞 (DC)与正常人来源DC在形态、表型的差异 ,为主动特异性免疫治疗MM提供依据。
补充资料：多发性骨髓瘤
| 多发性骨髓瘤 multiple myeloma 浆细胞恶性增生性疾病。因为浆细胞主要在骨髓中，而且形成多发的瘤样浸润，故称MM。单克隆恶性浆细胞（即骨髓瘤细胞）的无限制增殖，可产生一种破骨细胞活化因子引起溶骨破坏和骨折；影响骨髓的造血功能，导致贫血和出血；产生大量单克隆免疫球蛋白（Ig），也称M蛋白，而正常 Ig明显下降，结果血液粘稠度可增高，并易患感染；由于轻链自尿中排出（尿本-周氏蛋白 ）及高钙血症等，常导致肾功能损害。本病原因未明，好发于50岁以上的老年人，自然病程1～2年。但由于化疗等技术的改进，生存期明显延长，少数可达10年以上。本病的特征性检查是：①骨髓中浆细胞增高大于10％，一般大于20％，并可见双核或三核浆细胞；②血清单株Ig异常增高，MM常以此分型，以IgG型最常见，IgA型和轻链型次之，IgD型少见，个别为IgE型和不分泌或不产生Ig型；③骨骼X线见骨质破坏、病理性骨折和骨质稀疏等。上面 3项中有两项阳性即可诊断。但早期或不典型病例易误诊为肾炎、再生障碍性贫血、肝硬变和骨转移瘤。除支持和对症治疗外，主要是联合化疗, M2方案是诱导缓解首选方案，无效或复发者可用VAD方案，放疗对局部骨折和缓解疼痛有效。用干扰素α-2b治疗MM取得显著疗效。 |
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参考词条