1) Cx43 gene knockout mice
Cx43基因敲除小鼠
2) Knockout mice
基因敲除小鼠
1.
[Objective] To observe the dynamic changes of bone mineral density at different bone sites of glucose-dependent insulinotropic polypeptide (GIP) receptor knockout mice (GIPR-/- mice) and to explore the possible effects of GIP on bone turnover in mice.
【目的】观察葡萄糖依赖性促胰岛素多肽(GIP)受体基因敲除小鼠(GIPR-/-小鼠)不同部位骨密度的动态改变。
3) Nurr1 knock-out(Nurr1+/-) mice
Nurr1基因敲除小鼠
4) gene knockout mice
基因敲除小鼠
1.
Objective To observe the effect of Zhixinkang Capsule (ZXKC) on serum TNF-α和IL-1β of Apolipoprotein E (ApoE)-gene knockout mice.
目的观察脂欣康胶囊对载脂蛋白E(ApoE)基因敲除小鼠血清肿瘤坏死因子α(TNF-α)和白细胞介素1β(IL-1β)的影响。
5) Lats1 gene knockout mice
Lats1基因敲除小鼠
1.
ObjectiveThe Lats1 gene knockout mice were selected as an example to study the technology on germplasm storage of the genetic mice in Resource Bank of National Genetic Mice.
目的 以Lats1基因敲除小鼠为例 ,研究国家遗传工程小鼠资源库遗传小鼠的保种技术路线及方法。
6) Double knockout mice
双基因敲除小鼠
1.
To investigate the effects of EUK4010 on the neurodegenerative phenotypes of Presenilin-1/Presenilin-2 double knockout mice,10μg/g of body weight of EUK4010 was administrated on Presenilin-1/Presenilin-2 double knockout mice at 2—7 months and 6—11 months,respectively.
为了研究本实验室筛选出的单体化合物EUK4010对Presenilin-1/Presenilin-2双基因敲除小鼠神经退行性症状的作用及机制,将EUK4010(10μg/g体重)分别作用于2月龄和6月龄的双基因敲除小鼠(dKO小鼠),通过组织学、实时荧光定量PCR及Western blot、行为学等方法发现该化合物对dKO小鼠的体重下降、脑室扩大、海马萎缩等有一定缓解作用,但对dKO小鼠认知行为的改变尚不明显。
补充资料：敲杀
1.打死。
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